IL-22 R alpha 1

IL-22 R alpha 1 Molekülinformation

Englischer Name	Interleukin-22 receptor	Anzahl der inverkehr gebrachten Arzneimittel	0
Anzahl der klinischen Arzneimittel	5	Target-Alias
Höchste Forschungs- und Entwicklungsphase	Phase 2 Clinical

Englischer Name	Interleukin-22 receptor
Target-Alias
Anzahl der inverkehr gebrachten Arzneimittel	0
Anzahl der klinischen Arzneimittel	5
Höchste Forschungs- und Entwicklungsphase	Phase 2 Clinical

IL-22 R alpha 1 Produktliste

Attribut
Protein (5)
Produktbibliothek
Online (5)
Spezies
Mouse (1)Cynomolgus (1)Human (3)
Etikett
His Tag (3)Fc Tag (1)His Tag & Avi Tag (1)
Marker
Unconjugated (4)Biotin-labeled (1)

Produktnummer	Spezies	Expressionssystem	Produktbeschreibung	Vorbestellen/Bestellen
IL1-H5257	Human	HEK293	Human IL-22 R alpha 1 Superstable Mutant Protein, Fc Tag (MALS verified)	In den Warenkorb legen
IL1-H52H7	Human	HEK293	Human IL-22 R alpha 1 Superstable Mutant Protein, His Tag (MALS & SPR verified)	In den Warenkorb legen
IL1-H82E5	Human	HEK293	Biotinylated Human IL-22 R alpha 1 Superstable Mutant Protein, His,Avitag™ (HPLC verified)	In den Warenkorb legen
IL1-M52H8	Mouse	HEK293	Mouse IL-22 R alpha 1 Protein, His Tag (MALS & SPR verified)	In den Warenkorb legen
IL1-C52H7	Cynomolgus	HEK293	Cynomolgus IL-22 R alpha 1 Protein, His Tag (MALS & SPR verified)	In den Warenkorb legen

Gesamtmenge5

IL-22 R alpha 1 Molekülhintergrund

Interleukin-22 receptor subunit alpha-1(IL22RA1) is a component of the receptor for IL20, IL22 and IL24.Component of IL22 receptor formed by IL22RA1 and IL10RB enabling IL22 signaling via JAK/STAT pathways. IL22 also induces activation of MAPK1/MAPK3 and Akt kinases pathways. Component of one of the receptor for IL20 and IL24 formed by IL22RA1 and IL20RB also signaling through STATs activation. Mediates IL24 antiangiogenic activity as well as IL24 inhibitory effect on endothelial cell tube formation and differentiation.

Klinische Arzneimittelinformation

Englischer Name	Forschungscode	Forschungsphase	Firma	Indikationen	Klinische Studie
Efmarodocokin alfa	RO-7021610; UTTR-1147A; RG-7880	Phase 2 Clinical	Genentech Inc	Colitis, Ulcerative; Coronavirus Disease 2019 (COVID-19); Crohn Disease; Diabetic Foot; Graft vs Host Disease	Details
Temtokibart	ARGX-112; LEO-138559; LP-0145	Phase 2 Clinical	Argenx Se, Leo Pharma Inc	Dermatitis, Atopic	Details
CK-0045	CK-0045	Phase 2 Clinical	Cytoki Pharma ApS	Diabetes Mellitus, Type 2; Obesity; Overweight	Details
Eflepedocokin alfa	F-652	Phase 2 Clinical	Evive Biotech Ltd	Acute-On-Chronic Liver Failure; Coronavirus Disease 2019 (COVID-19); Enteritis; Enterocolitis, Necrotizing; Graft vs Host Disease; Hepatitis, Alcoholic; Pancreatitis	Details
ABBV-022	ABBV-022	Phase 1 Clinical	Abbvie Inc	Colitis, Ulcerative	Details