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Fc gamma RI / CD64

Fc gamma RI / CD64 Molekülinformation

Englischer NameHigh affinity immunoglobulin gamma Fc receptor IAnzahl der inverkehr gebrachten Arzneimittel0
Anzahl der klinischen Arzneimittel0Target-AliasIgG Fc Receptor I,FcgammaRIa,High Affinity Immunoglobulin Gamma Fc Receptor I,Fc-Gamma Receptor I A1,CD64 Antigen,CD64A,CD64,FCG1,FCGR1,IGFR1,FcRI,Fc-gamma RIA,Fc-gamma RI,Fc Fragment Of IgG Receptor Ia,Fc Fragment Of IgG, High Affinity Ia, Receptor (CD64),Fc Gamma Receptor Ia,FCGR1A,Fc Fragment Of IgG, High Affinity Ia, Receptor For (CD64)
Höchste Forschungs- und EntwicklungsphasePreclinical
Englischer NameHigh affinity immunoglobulin gamma Fc receptor I
Target-AliasIgG Fc Receptor I,FcgammaRIa,High Affinity Immunoglobulin Gamma Fc Receptor I,Fc-Gamma Receptor I A1,CD64 Antigen,CD64A,CD64,FCG1,FCGR1,IGFR1,FcRI,Fc-gamma RIA,Fc-gamma RI,Fc Fragment Of IgG Receptor Ia,Fc Fragment Of IgG, High Affinity Ia, Receptor (CD64),Fc Gamma Receptor Ia,FCGR1A,Fc Fragment Of IgG, High Affinity Ia, Receptor For (CD64)
Anzahl der inverkehr gebrachten Arzneimittel0
Anzahl der klinischen Arzneimittel0
Höchste Forschungs- und EntwicklungsphasePreclinical

Fc gamma RI / CD64 Molekülhintergrund

Receptors that recognize the Fc portion of IgG are divided into three groups designated Fc gamma RI, RII, and RIII, also known respectively as CD64, CD32, and CD16. Fc gamma RI binds IgG with high affinity and functions during early immune responses. Fc gamma RII and RIII are low affinity receptors that recognize IgG as aggregates surrounding multivalent antigens during late immune responses. High affinity immunoglobulin gamma Fc receptor I is also known as FCGR1A, FCG1, FCGR1, CD64 and IGFR1, is a type of integral membrane glycoprotein that binds monomeric IgG-type antibodies with high affinity, which belongs to the immunoglobulin superfamily or FCGR1 family. FCGR1A / CD64 contains 3 Ig-like C2-type (immunoglobulin-like) domains. CD64 is constitutively found on only macrophages and monocytes, but treatment of polymorphonuclear leukocytes with cytokines like IFNγ and G-CSF can induce CD64 expression on these cells.

Fc gamma RI / CD64 Molekülalias

FCGR1A,FCG1,FCGR1,IGFR1,CD64,CD64A,FCRI

Produktrezensionen

  • g***t2025-11-29
    0Menschen mögen
    Very good product for SPR analyses with antibodies
  • H***n2023-05-03
    0Menschen mögen
    I used Acro's Fc gamma receptors to build several new antibody binding assays. The proteins arrived promptly, sometimes within a few days of placing the orders. The proteins were also high quality, with no background or issues with stability. I have continued to use them for months with no issues. These produced high quality and robust data with minimal assay development. I would highly recommend this product.
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