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Cadherin-3

Cadherin-3 Overview

English Name	Cadherin 3	Approved Drugs	0
Drugs in Clinical Trials	7	Target Synonym	Cadherin 3， Type 1， P-Cadherin (Placental)，Placental Cadherin，CDHP，P-cadherin，CDH3，Cadherin 3，Calcium-Dependent Adhesion Protein， Placental，Cadherin 3， P-Cadherin (Placental)，Cadherin-3，HJMD，PCAD
Highest Development Stage	Phase 2 Clinical

English Name	Cadherin 3
Target Synonym	Cadherin 3， Type 1， P-Cadherin (Placental)，Placental Cadherin，CDHP，P-cadherin，CDH3，Cadherin 3，Calcium-Dependent Adhesion Protein， Placental，Cadherin 3， P-Cadherin (Placental)，Cadherin-3，HJMD，PCAD
Approved Drugs	0
Drugs in Clinical Trials	7
Highest Development Stage	Phase 2 Clinical

Cadherin-3 Product List

Product Category
Protein (3)
Product Status
Launched (3)
Species
Human (1)Mouse (1)Cynomolgus (1)
Tag
His Tag (3)
Conjugate
Unconjugated (3)

Cat. No.	Species	Host	Product Description
CA3-H52H3	Human	HEK293	Human Cadherin-3 Protein, His Tag, low endotoxin
CA3-M52H3	Mouse	HEK293	Mouse Cadherin-3 Protein, His Tag
CA3-C52H3	Cynomolgus	HEK293	Cynomolgus Cadherin-3 Protein, His Tag

Total: 3

Cadherin-3 Background

Cadherin-3 （also known as P-cadherin）is a classical cell-to-cell adhesion molecule with a homeostatic function in several normal tissues. In humans, cadherin-3 is only detected in a few organs. However, its overexpression is strongly associated with a poor prognosis in some solid tumors including breast, lung and pancreatic cancers.

Cadherin-3 Synonyms

CDH3,CDHP,Cadherin-3,P-cadherin

Clinical Drug Information

English Name	Research Code	Highest Development Stage	Company	Indication	Clinical Trial
STEMVAC	EP-101	Phase 2 Clinical	Epithany	Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; HR-positive breast cancer; Lung Neoplasms; Triple Negative Breast Neoplasms	Details
BC-3195	BC3195; BC-3195	Phase 2 Clinical	Wuxi BioCity	Neoplasm Metastasis; Neoplasms; Solid tumours	Details
FF-21101-Y-90	FF-21101-Y-90; PPMX-T002	Phase 1 Clinical	Fujifilm Holdings Corp	Solid tumours	Details
FF-21101	FF-21101	Phase 1 Clinical	Perseus Proteomics Inc	Bile Duct Neoplasms; Colorectal Neoplasms; Head and Neck Neoplasms; Ovarian Neoplasms; Pancreatic Neoplasms; Solid tumours	Details
TRAILR2/CDH3 bispecific antibody (Boehringer Ingelheim)		Phase 1 Clinical	Boehringer Ingelheim International Gmbh	Neoplasms	Details
AMG 305	AMG 305; AMG-305	Phase 1 Clinical	Amgen Inc	Solid tumours	Details
FF-21101In	FF-21101In	Phase 1 Clinical	PeptiDream Inc	Solid tumours	Details