VEGF-D

VEGF-D Molekülinformation

Englischer Name	Vascular endothelial growth factor D	Anzahl der inverkehr gebrachten Arzneimittel	0
Anzahl der klinischen Arzneimittel	2	Target-Alias	C-Fos Induced Growth Factor (Vascular Endothelial Growth Factor D)，FIGF，c-Fos-induced growth factor，VEGFD，VEGF-D，Vascular Endothelial Growth Factor D
Höchste Forschungs- und Entwicklungsphase	Phase 2 Clinical

Englischer Name	Vascular endothelial growth factor D
Target-Alias	C-Fos Induced Growth Factor (Vascular Endothelial Growth Factor D)，FIGF，c-Fos-induced growth factor，VEGFD，VEGF-D，Vascular Endothelial Growth Factor D
Anzahl der inverkehr gebrachten Arzneimittel	0
Anzahl der klinischen Arzneimittel	2
Höchste Forschungs- und Entwicklungsphase	Phase 2 Clinical

VEGF-D Produktliste

Attribut
Protein (5)
Produktbibliothek
Online (5)
Spezies
Human (2)Cynomolgus (1)Mouse (2)
Etikett
His Tag (2)His Tag & Avi Tag (2)Fc Tag (1)
Marker
Unconjugated (3)Biotin-labeled (2)

Produktnummer	Spezies	Expressionssystem	Produktbeschreibung	Vorbestellen/Bestellen
HOT VED-H5228	Human	HEK293	Human VEGF-D Protein, His Tag	In den Warenkorb legen
HOT VED-H52H3	Human	HEK293	Human VEGF-D Protein, His Tag (MALS verified)	In den Warenkorb legen
HOT VED-M82E4	Mouse	HEK293	Biotinylated Mouse VEGF-D Protein, His,Avitag™	In den Warenkorb legen
VED-M5253	Mouse	HEK293	Mouse VEGF-D Protein, Fc Tag	In den Warenkorb legen
VED-C82E3	Cynomolgus	HEK293	Biotinylated Cynomolgus VEGF-D Protein, His,Avitag™	In den Warenkorb legen

Gesamtmenge5

VEGF-D Molekülhintergrund

Vascular endothelial growth factor D (VEGF-D) is also known as C-fos induced growth factor (FIGF), which belongs to the PDGF / VEGF growth factor family and is active in angiogenesis, lymphangiogenesis, and endothelial cell growth, stimulating their proliferation and migration and also has effects on the permeability of blood vessels. This secreted protein VEGF-D / FIGF undergoes a complex proteolytic maturation, generating multiple processed forms that bind and activate VEGFR-2 and VEGFR-3. The structure and function of this protein is similar to those of VEGFC. FIGF / VEGF-D is highly expressed in lung, heart, small intestine and fetal lung. FIGF / VEGF-D may function in the formation of the venous and lymphatic vascular systems during embryogenesis, and also in the maintenance of differentiated lymphatic endothelium in adults. Binds and activates VEGFR-2 (KDR / FLK1) and VEGFR-3 (FLT4) receptors.

VEGF-D Molekülalias

FIGF,VEGFD

Klinische Arzneimittelinformation

Englischer Name	Forschungscode	Forschungsphase	Firma	Indikationen	Klinische Studie
EG-016	EG-016; Ad-VEGF-A	Phase 2 Clinical	Ark Therapeutics Ltd	Peripheral Vascular Diseases	Details
EG-011	EG-011; Ad-VEGF-D	Phase 2 Clinical	Ark Therapeutics Ltd	Angina Pectoris	Details