STEAP1

STEAP1 Molekülinformation

Englischer Name	Six-transmembrane epithelial antigen of the prostate 1	Anzahl der inverkehr gebrachten Arzneimittel	0
Anzahl der klinischen Arzneimittel	7	Target-Alias	PRSS24，Six-transmembrane epithelial antigen of prostate 1，STEAP，STEAP1，STEAP Family Member 1，Six Transmembrane Epithelial Antigen Of The Prostate 1，STEAP1 Metalloreductase，Six Transmembrane Epithelial Antigen Of The Prostate，Metalloreductase STEAP1，EC 1.16.1.-，EC:1.16.1.-
Höchste Forschungs- und Entwicklungsphase	Phase 3 Clinical

Englischer Name	Six-transmembrane epithelial antigen of the prostate 1
Target-Alias	PRSS24，Six-transmembrane epithelial antigen of prostate 1，STEAP，STEAP1，STEAP Family Member 1，Six Transmembrane Epithelial Antigen Of The Prostate 1，STEAP1 Metalloreductase，Six Transmembrane Epithelial Antigen Of The Prostate，Metalloreductase STEAP1，EC 1.16.1.-，EC:1.16.1.-
Anzahl der inverkehr gebrachten Arzneimittel	0
Anzahl der klinischen Arzneimittel	7
Höchste Forschungs- und Entwicklungsphase	Phase 3 Clinical

STEAP1 Produktliste

Attribut
Cell (2)Protein (5)
Produktbibliothek
Online (7)
Spezies
Human (6)Rat (1)
Etikett
- (2)His Tag & Strep Tag (2)Tag Free (1)His Tag & Avi Tag & Flag Tag (1)His Tag & Flag Tag (1)
Marker
- (2)Unconjugated (4)Biotin-labeled (1)

Produktnummer	Spezies	Expressionssystem	Produktbeschreibung	Vorbestellen/Bestellen
HOT CHEK-ATP154	Human	HEK293	HEK293/Human STEAP1 Stable Cell Line	In den Warenkorb legen
HOT ST1-H5283	Human	HEK293	Human STEAP1 Full Length Protein, Twin-Strep,His Tag (Detergent) (SPR verified)	In den Warenkorb legen
HOT ST1-H82D3	Human	HEK293	Biotinylated Human STEAP1 Full Length Protein, Avitag™,Flag&His Tag (Detergent)	In den Warenkorb legen
SCCHO-ATP121	Human	CHO	CHO/Human STEAP1 Stable Cell Line	In den Warenkorb legen
ST1-H5286	Human	HEK293	Human STEAP1 Full Length Protein, Twin-Strep,His Tag (Nanodisc)	In den Warenkorb legen
ST1-H52P3	Human	HEK293	Human STEAP1 Full Length Protein (VLP)	In den Warenkorb legen
ST1-R52D3	Rat	HEK293	Rat STEAP1 Protein, Flag,His Tag (Detergent)	In den Warenkorb legen

Gesamtmenge7

STEAP1 Molekülhintergrund

Six-transmembrane epithelial antigen of the prostate 1 (STEAP1) is an integral membrane protein that is highly up-regulated on the cell surface of several human cancers, making it a promising therapeutic target to manage these diseases. It shares sequence homology with three enzymes (STEAP2-STEAP4) that catalyze the NADPH-dependent reduction of iron(III). Taking into account its high specificity and overexpression in human cancers, STEAP1 is nowadays a promising candidate to be imposed as a therapeutic target.

STEAP1 Molekülalias

STEAP1, PRSS24, STEAP

Klinische Arzneimittelinformation

Englischer Name	Forschungscode	Forschungsphase	Firma	Indikationen	Klinische Studie
Xaluritamig	AMG-509	Phase 3 Clinical	Amgen Inc, Xencor Inc	Castration-Sensitive Prostate Neoplasms; Hormone-Sensitive Prostate Neoplasms; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Sarcoma, Ewing	Details
89Zr-DFO-MSTP2109A		Phase 2 Clinical	Genentech Inc, Memorial Sloan Kettering Cancer Center	Prostatic Neoplasms	Details
STEAP1 CART Cell Therapy(PromiCell)		Phase 2 Clinical	Fred Hutchinson Cancer Research Center, PromiCell Therapeutics Inc	Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant	Details
PRO CAR-201A	PRO CAR-201A	Phase 1 Clinical	Fred Hutchinson Cancer Research Center	Prostatic Neoplasms, Castration-Resistant	Details
ABBV-969	ABBV-969; ABBV969	Phase 1 Clinical	Abbvie Inc	Prostatic Neoplasms, Castration-Resistant	Details
ADRX-0405	ADRX-0405	Phase 1 Clinical	Adcentrx Therapeutics Inc	Neoplasms; Solid tumours	Details
DXC-008	DAC-008; DXC-008	Phase 1 Clinical	Hangzhou Dac Biotech Company Ltd	Prostatic Neoplasms; Sarcoma, Ewing; Solid tumours	Details