Prolactin R

Prolactin R Molekülinformation

Englischer Name	Prolactin receptor	Anzahl der inverkehr gebrachten Arzneimittel	0
Anzahl der klinischen Arzneimittel	2	Target-Alias	PRL-R，PRLR，Prolactin Receptor，Secreted Prolactin Binding Protein，HPRL Receptor，RI-PRLR，HPRLrI，HPRL，MFAB，Receptors， Prolactin
Höchste Forschungs- und Entwicklungsphase	Phase 3 Clinical

Englischer Name	Prolactin receptor
Target-Alias	PRL-R，PRLR，Prolactin Receptor，Secreted Prolactin Binding Protein，HPRL Receptor，RI-PRLR，HPRLrI，HPRL，MFAB，Receptors， Prolactin
Anzahl der inverkehr gebrachten Arzneimittel	0
Anzahl der klinischen Arzneimittel	2
Höchste Forschungs- und Entwicklungsphase	Phase 3 Clinical

Prolactin R Produktliste

Attribut
Protein (6)
Produktbibliothek
Online (6)
Spezies
Human (3)Cynomolgus (1)Rat (1)Mouse (1)
Etikett
Fc Tag (1)His Tag (4)His Tag & Avi Tag (1)
Marker
Unconjugated (5)Biotin-labeled (1)

Produktnummer	Spezies	Expressionssystem	Produktbeschreibung	Vorbestellen/Bestellen
PRP-H5251	Human	HEK293	Human Prolactin R / PRLR Protein, Fc Tag	In den Warenkorb legen
PRR-H52Ha	Human	HEK293	Human Prolactin R / PRLR Protein, His Tag	In den Warenkorb legen
PRR-H82E3	Human	HEK293	Biotinylated Human Prolactin R / PRLR Protein, His,Avitag™ (MALS verified)	In den Warenkorb legen
PRR-M52H3	Mouse	HEK293	Mouse Prolactin R / PRLR Protein, His Tag (MALS & SPR verified)	In den Warenkorb legen
PRR-C52H3	Cynomolgus	HEK293	Cynomolgus Prolactin R Protein, His Tag (MALS verified)	In den Warenkorb legen
PRR-R52H3	Rat	HEK293	Rat Prolactin R / PRLR Protein, His Tag (MALS & SPR verified)	In den Warenkorb legen

Gesamtmenge6

Prolactin R Molekülhintergrund

As a transmembrane receptor, the prolactin receptor (PRL-R) interacts with prolactin. In addition, the PRL-R also binds and is activated by growth hormone (GH) and human placental lactogen (hPL). Preclinical investigations, epidemiological studies and analyses of tissue specimens from patients strongly support the contribution of prolactin receptor (PRLR) signaling to breast and prostate tumorigenesis and cancer progression. Moreover, The PRLR has been found to be essential for lobuloalveolar maturation of the mammary glands during pregnancy, as evidenced by the fact that PRLR knockout mice show severely impaired development of lobuloalveolar structures.

Prolactin R Molekülalias

Prolactin R,PRLR,PRL-R

Klinische Arzneimittelinformation

Englischer Name	Forschungscode	Forschungsphase	Firma	Indikationen	Klinische Studie
BAY-1158061	BAY-1158061; HMI-115	Phase 3 Clinical	Bayer AG	Alopecia; Endometriosis; Pain	Details
ABS-201	ABS-201	Phase 2 Clinical	Absci Corp	Alopecia; Skin Diseases	Details