NKp46

NKp46 Molekülinformation

Englischer Name	Natural cytotoxicity triggering receptor 1	Anzahl der inverkehr gebrachten Arzneimittel	0
Anzahl der klinischen Arzneimittel	3	Target-Alias	NK cell-activating receptor，NK-p46，Lymphocyte antigen 94 homolog，NKp46，hNKp46，Lymphocyte Antigen 94 Homolog (Activating NK-Receptor; NK-P46)，Natural killer cell p46-related protein，LY94，Lymphocyte Antigen 94 (Mouse) Homolog (Activating NK-Receptor; NK-P46)，CD335 Antigen，CD335
Höchste Forschungs- und Entwicklungsphase	Phase 2 Clinical

Englischer Name	Natural cytotoxicity triggering receptor 1
Target-Alias	NK cell-activating receptor，NK-p46，Lymphocyte antigen 94 homolog，NKp46，hNKp46，Lymphocyte Antigen 94 Homolog (Activating NK-Receptor; NK-P46)，Natural killer cell p46-related protein，LY94，Lymphocyte Antigen 94 (Mouse) Homolog (Activating NK-Receptor; NK-P46)，CD335 Antigen，CD335
Anzahl der inverkehr gebrachten Arzneimittel	0
Anzahl der klinischen Arzneimittel	3
Höchste Forschungs- und Entwicklungsphase	Phase 2 Clinical

NKp46 Produktliste

Attribut
Protein (16)Cell (2)Antibody (1)
Produktbibliothek
Online (19)
Spezies
Human (12)Cynomolgus (3)Mouse (4)
Etikett
Fc Tag (4)His Tag (6)Llama IgG Fc Tag (2)Fc Tag & Avi Tag (1)His Tag & Avi Tag (3)- (2)Tag Free (1)
Marker
Unconjugated (10)Biotin-labeled (5)- (2)PE Labeled (1)FITC Labeled (1)

Produktnummer	Spezies	Expressionssystem	Produktbeschreibung	Vorbestellen/Bestellen
HOT NC1-H52H4	Human	HEK293	Human NKp46 / NCR1 / CD335 Protein, His Tag, low endotoxin (MALS verified)	In den Warenkorb legen
HOT NC1-H52H6	Human	HEK293	Human NKp46 / NCR1 / CD335 Protein, His Tag	In den Warenkorb legen
HOT NK6-H82E2	Human	HEK293	Biotinylated Human NKp46 / NCR1 / CD335 Protein, His Tag, ultra sensitivity (primary amine labeling)	In den Warenkorb legen
HOT NP6-H82H3	Human	HEK293	Biotinylated Human NKp46 / NCR1 / CD335 Protein, His,Avitag™, premium grade	In den Warenkorb legen
CHEK-ATP153	Human	HEK293	HEK293/Human NKp46 Stable Cell Line	In den Warenkorb legen
NC1-H5255	Human	HEK293	Human NKp46 / NCR1 / CD335 Protein, Llama IgG2b Fc Tag, low endotoxin	In den Warenkorb legen
NC1-H5257	Human	HEK293	Human NKp46 / NCR1 / CD335 Protein, Fc Tag, premium grade	In den Warenkorb legen
NC1-H5258	Human	HEK293	Human NKp46 / NCR1 / CD335 Protein, Fc Tag	In den Warenkorb legen
NC1-H5259	Human	HEK293	Human NKp46 / NCR1 / CD335 Protein, Fc Tag	In den Warenkorb legen
NC1-H82F9	Human	HEK293	Biotinylated Human NKp46 / NCR1 / CD335 Protein, Fc,Avitag™, premium grade	In den Warenkorb legen

Gesamtmenge19

NKp46 Molekülhintergrund

Natural cytotoxicity triggering receptor 1 (NCR1) is also known as Natural killer cell p46-related protein (NK-p46), Lymphocyte antigen 94 homolog (LY94), CD antigen CD335, which belongs to the natural cytotoxicity receptor (NCR) family. NCR1 contains two Ig-like (immunoglobulin-like) domains. NCR1 interacts with CD247 and FCER1G. NCR1 / CD335 may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis.

NKp46 Molekülalias

NCR1,LY94,CD335,NK-p46,hNKp46

Klinische Arzneimittelinformation

Englischer Name	Forschungscode	Forschungsphase	Firma	Indikationen	Klinische Studie
NY-303	NY-303	Phase 2 Clinical	NAYA Biosciences Inc	Carcinoma, Hepatocellular; Solid tumours	Details
IPH-6501	IPH-6501; IPH-65	Phase 2 Clinical	Innate Pharma SA	Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Neoplasms	Details
SAR-443579	SAR-443579; SAR443579; SAR'579; IPH6101; IPH-6101	Phase 1 Clinical	Sanofi	Blastic Plasmacytoid Dendritic Cell Neoplasm; Hematologic Diseases; Leukemia, B-Cell; Leukemia, Myeloid, Acute; Myelodysplastic Syndromes; Precursor Cell Lymphoblastic Leukemia-Lymphoma	Details