MIF

MIF Molekülinformation

Englischer Name	Macrophage migration inhibitory factor	Anzahl der inverkehr gebrachten Arzneimittel	1
Anzahl der klinischen Arzneimittel	3	Target-Alias	EC:5.3.2.1，GIF，EC 5.3.3.12，EC 5.3.2.1，Macrophage Migration-Inhibitory Factors，Epididymis Secretory Sperm Binding Protein，EC:5.3.3.12，Phenylpyruvate Tautomerase，L-Dopachrome Tautomerase，MMIF，Glycosylation-inhibiting factor，L-dopachrome isomerase，MIF，Macrophage Migration Inhibitory Factor，Macrophage Migration Inhibitory Factor (Glycosylation-Inhibiting Factor)，GLIF
Höchste Forschungs- und Entwicklungsphase	Approved

Englischer Name	Macrophage migration inhibitory factor
Target-Alias	EC:5.3.2.1，GIF，EC 5.3.3.12，EC 5.3.2.1，Macrophage Migration-Inhibitory Factors，Epididymis Secretory Sperm Binding Protein，EC:5.3.3.12，Phenylpyruvate Tautomerase，L-Dopachrome Tautomerase，MMIF，Glycosylation-inhibiting factor，L-dopachrome isomerase，MIF，Macrophage Migration Inhibitory Factor，Macrophage Migration Inhibitory Factor (Glycosylation-Inhibiting Factor)，GLIF
Anzahl der inverkehr gebrachten Arzneimittel	1
Anzahl der klinischen Arzneimittel	3
Höchste Forschungs- und Entwicklungsphase	Approved

MIF Produktliste

Attribut
Protein (1)
Produktbibliothek
Online (1)
Spezies
Human (1)
Etikett
His Tag & Avi Tag (1)
Marker
Biotin-labeled (1)

Produktnummer	Spezies	Expressionssystem	Produktbeschreibung	Proteinstruktur	Reinheit	Eigenschaften	Vorbestellen/Bestellen
MIF-H82E7	Human	HEK293	Biotinylated Human MIF Protein, His,Avitag™				In den Warenkorb legen

Gesamtmenge1

Produktanfrage

MIF Molekülhintergrund

Macrophage migration inhibitory factor(MIF) is also known as Glycosylation-inhibiting factor(GIF), L-dopachrome isomerase, L-dopachrome tautomerase, Phenylpyruvate tautomerase. Interacts with CXCR2 extracellular domain, CD74 extracellular domain, COPS5 and BNIPL. The expression of MIF at sites of inflammation suggests a role as mediator in regulating the function of macrophages in host defense. Counteracts the anti-inflammatory activity of glucocorticoids. Has phenylpyruvate tautomerase and dopachrome tautomerase activity (in vitro), but the physiological substrate is not known. It is not clear whether the tautomerase activity has any physiological relevance, and whether it is important for cytokine activity.

MIF Molekülalias

MIF,GLIF,MMIF,GIF

Klinische Arzneimittelinformation

Englischer Name	Forschungscode	Forschungsphase	Firma	Indikationen	Klinische Studie
IPG-1094	IPG-1094; IPG-001	Phase 2 Clinical	Nanjing Immunophage Biotech Co Ltd	Brain metastases; Brain Neoplasms; Hematologic Neoplasms; Lupus Nephritis; Multiple Myeloma; Multiple Sclerosis; Psoriasis; Solid tumours	Details
TRP2-electroporated autologous dendritic cell therapy (Memorial Sloan-Kettering)		Phase 1 Clinical	Memorial Sloan Kettering Cancer Center	Melanoma	Details
STP-1	STP-1; STP1	Phase 1 Clinical	Stalicla Sa	Autism Spectrum Disorder	Details

Inverkehr gebrachte Arzneimittelinformation

Englischer Name	Forschungscode	Forschungsphase	Firma	Frühestes Markenname	Frühestes Genehmigungsland	Früheste Indikation	Früheste Genehmigungsgesellschaft	Früheste Genehmigungsdatum	Indikationen	Klinische Studie
Ibudilast	KC-404; AV-411; MN-166	Approved	Kyorin Pharmaceutical Co Ltd	Ketas, Pinatos, Eyevinal	Japan	Asthma; Multiple Sclerosis; Neuralgia	Kyorin Pharmaceutical Co Ltd		Alcoholism; Amyotrophic Lateral Sclerosis; Asthma; Diabetic Neuropathies; Headache Disorders, Secondary; HIV Infections; Multiple Sclerosis; Multiple Sclerosis, Chronic Progressive; Neuralgia; Opioid-Related Disorders; Pneumonia, Viral; Substance-Related Disorders	Details

Produktrezensionen

S***n2023-04-28
0Menschen mögen
Biotinylated Human MIF Protein, His,Avitag™
This product was used for characterization of a novel therapeutic testing kinetics and affinity on SPR with a Cytiva BiotinCAPture kit. It worked phenomenally with both the novel approach and a positive control. Additionally, it was used with a Streptavidin coated ELISA plate (also from Acro), results were phenomenal with that approach as well. Overall, this product has been well received by our team and we have already ordered more to continue testing.