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LTBR

LTBR Molekülinformation

Englischer NameTumor necrosis factor receptor superfamily member 3Anzahl der inverkehr gebrachten Arzneimittel0
Anzahl der klinischen Arzneimittel1Target-AliasLymphotoxin-beta receptor,Tumor necrosis factor receptor type III,LTBR,Tumor necrosis factor receptor superfamily member 3,D12S370,TNFRSF3,TNFCR,TNFR3,TNFR Superfamily, Member 3,Lymphotoxin B Receptor,LT-BETA-R,TNF-R-III,TNFR2-RP,TNF-RIII,TNFR-III,TNFR-RP,Lymphotoxin beta Receptor,Tumor necrosis factor C receptor,Tumor Necrosis Factor Receptor 2-Related Protein,Lymphotoxin Beta Receptor (TNFR Superfamily, Member 3)
Höchste Forschungs- und EntwicklungsphasePhase 1 Clinical
Englischer NameTumor necrosis factor receptor superfamily member 3
Target-AliasLymphotoxin-beta receptor,Tumor necrosis factor receptor type III,LTBR,Tumor necrosis factor receptor superfamily member 3,D12S370,TNFRSF3,TNFCR,TNFR3,TNFR Superfamily, Member 3,Lymphotoxin B Receptor,LT-BETA-R,TNF-R-III,TNFR2-RP,TNF-RIII,TNFR-III,TNFR-RP,Lymphotoxin beta Receptor,Tumor necrosis factor C receptor,Tumor Necrosis Factor Receptor 2-Related Protein,Lymphotoxin Beta Receptor (TNFR Superfamily, Member 3)
Anzahl der inverkehr gebrachten Arzneimittel0
Anzahl der klinischen Arzneimittel1
Höchste Forschungs- und EntwicklungsphasePhase 1 Clinical

LTBR Produktliste

  • Attribut

    Protein (5)

  • Produktbibliothek

    Online (5)

  • Spezies

    Human (3)Cynomolgus (1)Mouse (1)

  • Etikett

    His Tag & Avi Tag (2)Fc Tag (1)His Tag (2)

  • Marker

    Biotin-labeled (1)Unconjugated (4)

LTBR Molekülhintergrund

Lymphotoxin-beta receptor (LTBR) is also known as Tumor necrosis factor receptor superfamily member 3 (TNFRSF3), Tumor necrosis factor receptor type III (TNF-RIII), which is a single-pass type I membrane protein containing four TNFR-Cys repeat regions. Except for interacting with HCV core protein, LTBR can not only associate with itself, but also can associate with TRAF3, TRAF4 and TRAF5. As the receptor for the heterotrimeric lymphotoxin containing LTA and LTB, and for TNFS14/LIGHT, LTBR promotes apoptosis via TRAF3 and TRAF5. Furthermore, LTBR may play a role in the development of lymphoid organs.

LTBR Molekülalias

LTBR,D12S370,TNFCR,TNFR3,TNFRSF3,TNFRIII

Klinische Arzneimittelinformation

Englischer NameForschungscodeForschungsphaseFirmaIndikationenKlinische Studie
RO-7567132RO7567132; RO-7567132; RG-6221; RG6221Phase 1 ClinicalF. Hoffmann-La Roche AgNeoplasms; Solid tumours
Details
  • Molekülinformation
  • Produktliste
  • Klinische Arzneimittelinformation
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