IL-5 R alpha

IL-5 R alpha Molekülinformation

Englischer Name	Interleukin-5 receptor subunit alpha	Anzahl der inverkehr gebrachten Arzneimittel	1
Anzahl der klinischen Arzneimittel	2	Target-Alias	Interleukin 5 Receptor， Alpha，Interleukin-5 Receptor Subunit Alpha，HSIL5R3，Interleukin-5 Receptor Alpha Chain，CDw125，Interleukin-5 Receptor alpha Subunit，Interleukin 5 Receptor Type 3，CD125 Antigen，Interleukin 5 Receptor Subunit Alpha，IL-5 Receptor Subunit Alpha，IL-5R-Alpha，IL5R，IL5RA，CD125，IL-5RA，IL-5R Subunit Alpha
Höchste Forschungs- und Entwicklungsphase	Approved

Englischer Name	Interleukin-5 receptor subunit alpha
Target-Alias	Interleukin 5 Receptor， Alpha，Interleukin-5 Receptor Subunit Alpha，HSIL5R3，Interleukin-5 Receptor Alpha Chain，CDw125，Interleukin-5 Receptor alpha Subunit，Interleukin 5 Receptor Type 3，CD125 Antigen，Interleukin 5 Receptor Subunit Alpha，IL-5 Receptor Subunit Alpha，IL-5R-Alpha，IL5R，IL5RA，CD125，IL-5RA，IL-5R Subunit Alpha
Anzahl der inverkehr gebrachten Arzneimittel	1
Anzahl der klinischen Arzneimittel	2
Höchste Forschungs- und Entwicklungsphase	Approved

IL-5 R alpha Produktliste

Attribut
Protein (4)
Produktbibliothek
Online (4)
Spezies
Human (3)Mouse (1)
Etikett
His Tag (2)Fc Tag (1)Fc Tag & Avi Tag (1)
Marker
Unconjugated (3)Biotin-labeled (1)

Produktnummer	Spezies	Expressionssystem	Produktbeschreibung	Vorbestellen/Bestellen
ILA-H5269	Human	HEK293	Human IL-5 R alpha / CD125 Protein, Fc Tag (MALS verified)	In den Warenkorb legen
ILA-H52H4	Human	HEK293	Human IL-5 R alpha / CD125 Protein, His Tag, low endotoxin (MALS & BLI verified)	In den Warenkorb legen
ILA-H82F5	Human	HEK293	Biotinylated Human IL-5 R alpha / CD125 Protein, Avitag™,Fc Tag (MALS verified)	In den Warenkorb legen
ILA-M52H7	Mouse	HEK293	Mouse IL-5 R alpha / CD125 Protein, His Tag (MALS & SPR verified)	In den Warenkorb legen

Gesamtmenge4

Produktanfrage

IL-5 R alpha Molekülhintergrund

Interleukin-5 receptor subunit alpha (IL5RA) is also known as IL-5 receptor subunit alpha, IL-5R subunit alpha and CD125,which is a single-pass type I membrane protein that belongs to the type I cytokine receptor family and type 5 subfamily.IL5R, a heterodimer of an alpha and a beta subunit, is expressed on eosinophils and basophils. IL5RA / CD125 is the receptor for interleukin-5 (IL5) and the alpha chain can bind to IL5. The WSXWS motif of IL5RA appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding.The beta subunit of IL5R is common to the IL3, IL5 and GM-CSF receptors.

IL-5 R alpha Molekülalias

IL5Ra,CD125

Klinische Arzneimittelinformation

Englischer Name	Forschungscode	Forschungsphase	Firma	Indikationen	Klinische Studie
IL-5 CAR-T Cell Therapy (Zhejiang University)		Phase 1 Clinical	Zhejiang University	Hematologic Diseases; Neoplasms	Details
Trabikibart	CSL-311	Phase 1 Clinical	Csl Ltd	Asthma	Details

Inverkehr gebrachte Arzneimittelinformation

Englischer Name	Forschungscode	Forschungsphase	Firma	Frühestes Markenname	Frühestes Genehmigungsland	Früheste Indikation	Früheste Genehmigungsgesellschaft	Früheste Genehmigungsdatum	Indikationen	Klinische Studie
Benralizumab	KHK-4563; MEDI-563; BIW-8405; BIW-8405-IL-5R	Approved	Biowa Inc, Medimmune Llc	Fasenra, 凡舒卓	United States	Asthma	Astrazeneca Ab	2017-11-14	Asthma; Asthma, Exercise-Induced; Bronchiectasis; Chronic Urticaria; Dermatitis; Dermatitis, Atopic; Drug Hypersensitivity Syndrome; Eczema; Eosinophilia; Eosinophilic Asthma; Eosinophilic Esophagitis; Eosinophilic gastroenteritis (EG); Eosinophilic Granulomatosis With Polyangiitis; Gastroenteritis; Genetic Diseases, Inborn; Granulomatosis with Polyangiitis; Hematologic Diseases; Hypereosinophilic Syndrome; Hypersensitivity; Hypersensitivity, Immediate; Immune System Diseases; Leukocyte Disorders; Nasal Polyps; Pemphigoid, Bullous; Pulmonary Disease, Chronic Obstructive; Respiratory Tract Diseases; Sinusitis; Skin Diseases; Skin Diseases, Eczematous; Skin Diseases, Genetic	Details