IL-17 RB Molekülinformation
Molecule Name
Interleukin-17 receptor B
Molekülalias
IL-17 RB,Interleukin-17 receptor B,Interleukin-17 receptor B,Cytokine receptor-like 4,IL-17 receptor homolog 1,IL-17Rh1,IL17Rh1,Interleukin-17B receptor,IL-17B receptor,IL17RB,CRL4, EVI27, IL17BR
Drug Development Progress
Anzahl der klinischen Arzneimittel1
Anzahl der inverkehr gebrachten Arzneimittel0
Höchste Forschungs- und EntwicklungsphasePhase 2 Clinical
Target-Alias
IL-17 receptor B，IL-17RB，Cytokine receptor-like 4，IL-17 receptor homolog 1，IL-17Rh1，IL17Rh1，Interleukin-17B receptor，IL-17B receptor
Molekülhintergrund
IL17RB (EVI27, IL17Rh1) is a single pass transmembrane receptor which belongs to IL17R family of cytokine receptors. It was found to be expressed in liver, brain, testis and lungs. The ligand for IL17RB is IL17E, also known as IL25. The five IL-17 receptors (IL17RA-IL17RE) exhibit considerable sequence divergence between one another, but all appear to contain extracellular domains composed of fibronectin type-III (FnIII) domains, and cytoplasmic SEF/IL-17R (SEFIR) domains that show loose homology to Toll/IL-1R (TLR) domains.
IL-17 RB Produktliste
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Klinische Arzneimittelinformation
| Englischer Name | Forschungscode | Forschungsphase | Firma | Indikationen | Klinische Studie |
|---|---|---|---|---|---|
| SM-17 | SM-17; SM17 | Phase 2 Clinical | Sinomab Bioscience Ltd | Asthma; Dermatitis, Atopic; Idiopathic Pulmonary Fibrosis; Inflammatory Bowel Diseases | Details |