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Product Details
Synonyms
IL-17 RB, Interleukin-17 receptor B, Interleukin-17 receptor B, Cytokine receptor-like 4, IL-17 receptor homolog 1, IL-17Rh1, IL17Rh1, Interleukin-17B receptor, IL-17B receptor, IL17RB, CRL4, EVI27, IL17BR
Source
Human IL-17 RB Protein, His Tag (ILB-H52H5) is expressed from human 293 cells (HEK293). It contains AA Arg 18 - Pro 292 (Accession # Q9NRM6-1).
Predicted N-terminus: Arg 18
Request for sequenceMolecular Characterization
Other Tags and Version Biotin & Other Labeled Version
This protein carries a polyhistidine tag at the C-terminus.
The protein has a calculated MW of 32.2 kDa. The protein migrates as 45-55 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin
Less than 1.0 EU per μg by the LAL method / rFC method.
Purity
>95% as determined by SDS-PAGE.
>90% as determined by SEC-HPLC.
Formulation
Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.
Contact us for customized product form or formulation.
Reconstitution
Please see Certificate of Analysis for specific instructions.
For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
Shipping and Storage
This product is shipped at ambient temperature.
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
- -20°C to -70°C for 12 months in lyophilized state;
- -70°C for 3 months under sterile conditions after reconstitution.
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Data Display
SDS-PAGE
Human IL-17 RB Protein, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95% (With Star Ribbon Pre-stained Protein Marker).
SEC-HPLC
The purity of Human IL-17 RB Protein, His Tag (Cat. No. ILB-H52H5) was greater than 90% as determined by SEC-HPLC.
Bioactivity-ELISA
Immobilized Human IL-17 RB Protein, His Tag (Cat. No. ILB-H52H5) at 5 μg/mL (100 μL/well) can bind Biotinylated Human IL-17E Protein, His,Avitag (Cat. No. IL5-H82E1) with a linear range of 0.2-10 ng/mL (QC tested).
Protocol
User Reviews Publish Comment
Background Introduction
Frontier Progress
Drug Development Progress- English Name：
Interleukin-17 receptor B
- Category：
- Listed Drugs Count：
0 Details
- Clinical Drugs Count：
1 Details
- Highest R&D Stage：
Phase 2 Clinical
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