GDF-8

GDF-8 Molekülinformation

Englischer Name	Growth/differentiation factor 8	Anzahl der inverkehr gebrachten Arzneimittel	0
Anzahl der klinischen Arzneimittel	8	Target-Alias	MSTN，GDF-8，GDF8，Growth Differentiation Factor 8，MSLHP，Myostatin，Growth/Differentiation Factor 8
Höchste Forschungs- und Entwicklungsphase	NDA/BLA

Englischer Name	Growth/differentiation factor 8
Target-Alias	MSTN，GDF-8，GDF8，Growth Differentiation Factor 8，MSLHP，Myostatin，Growth/Differentiation Factor 8
Anzahl der inverkehr gebrachten Arzneimittel	0
Anzahl der klinischen Arzneimittel	8
Höchste Forschungs- und Entwicklungsphase	NDA/BLA

GDF-8 Produktliste

Attribut
Protein (10)
Produktbibliothek
Online (10)
Spezies
Human (5)Human / Mouse / Rat (1)Mouse (2)Cynomolgus (2)
Etikett
His Tag (5)Tag Free (1)His Tag & Avi Tag (3)Avi Tag (1)
Marker
Unconjugated (5)Biotin-labeled (5)

Produktnummer	Spezies	Expressionssystem	Produktbeschreibung	Vorbestellen/Bestellen
HOT GD8-H5243	Human	HEK293	Human latent GDF-8 Protein, His Tag, low endotoxin (pro & latent) (MALS verified)	In den Warenkorb legen
HOT GD8-H5343	Human	CHO	Human latent GDF-8 Protein, His Tag, low endotoxin (MALS verified)	In den Warenkorb legen
HOT GD8-H5344	Human / Mouse / Rat	CHO	Human / Mouse / Rat GDF-8 Protein, Tag Free	In den Warenkorb legen
GD8-H8243	Human	HEK293	Biotinylated Human latent GDF-8 Protein, His Tag, ultra sensitivity (primary amine labeling) (pro & latent) (MALS verified)	In den Warenkorb legen
GD8-H82Q3	Human	HEK293	Biotinylated Human latent GDF-8 Protein, His,Avitag™ (pro & latent)	In den Warenkorb legen
GD8-H8313	Human	CHO	Biotinylated Human GDF-8 Protein, Avitag™	In den Warenkorb legen
GD8-M5243	Mouse	HEK293	Mouse latent GDF-8 Protein, His Tag, low endotoxin	In den Warenkorb legen
GD8-M82Q3	Mouse	HEK293	Biotinylated Mouse latent GDF-8 Protein, Avitag™,His Tag	In den Warenkorb legen
GD8-C5243	Cynomolgus	HEK293	Cynomolgus Latent GDF-8 Protein, His Tag, low endotoxin	In den Warenkorb legen
GD8-C82Q3	Cynomolgus	HEK293	Biotinylated Cynomolgus latent GDF-8 Protein, Avitag™,His Tag	In den Warenkorb legen

Gesamtmenge10

GDF-8 Molekülhintergrund

Growth differentiation factor 8 (GDF8), also known as myostatin, is a unique member of the transforming growth factor-β superfamily that is expressed in human granulosa cells and has important roles in regulating a variety of ovarian functions. GDF8 acts as a negative regulator of skeletal muscle growth and differentiation. In addition to the expression in the musculoskeletal system, GDF8 is also expressed in various tissues, including the reproductive system.

GDF-8 Molekülalias

GDF-8, Myostatin, GDF8, MSTN, Growth,differentiation factor 8

Klinische Arzneimittelinformation

Englischer Name	Forschungscode	Forschungsphase	Firma	Indikationen	Klinische Studie
Talditercept alfa	RO-7239361; BMS-986089; RG-6206; BHV-2000	Phase 3 Clinical	Bristol-Myers Squibb Company	Muscular Atrophy, Spinal; Muscular Dystrophy, Duchenne; Neuromuscular Diseases; Obesity; Overweight	Details
Emugrobart	GYM-329; RG-6237; RG-70240; RO-7204239	Phase 3 Clinical	Chugai Pharmaceutical Co Ltd	Diabetes Mellitus, Type 2; Muscular Atrophy, Spinal; Muscular Dystrophy, Facioscapulohumeral; Obesity; Overweight	Details
Trevogrumab	REGN-1033; REGN1033; SAR-391786; GDF8	Phase 2 Clinical	Regeneron Pharmaceuticals Inc	Myositis, Inclusion Body; Obesity; Sarcopenia	Details
AAV1-FS344	AAV1-Follistatin; AAV1-FS344	Phase 2 Clinical	Nationwide Children'S Hospital	Becker muscular dystrophy; Muscular Dystrophy, Duchenne; Myositis, Inclusion Body	Details
EL-22	EL-22	Phase 1 Clinical		Obesity	Details
IBIO-600	IBIO-600	Phase 1 Clinical	AstralBio Inc	Obesity; Overweight	Details
Rinvatercept	RKER-065; KER-065	Phase 1 Clinical	Keros Therapeutics Inc	Neuromuscular Diseases; Obesity	Details
SRK-439	SRK-439	Phase 1 Clinical	Scholar Rock Inc	Heart Diseases; Obesity	Details