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Fc epsilon RI alpha

Fc epsilon RI alpha Molekülinformation

Englischer NameIgE Fc receptor, alpha-subunitAnzahl der inverkehr gebrachten Arzneimittel1
Anzahl der klinischen Arzneimittel1Target-AliasFc Fragment Of IgE, High Affinity I, Receptor For; Alpha Polypeptide,FCE1A,IgE Fc receptor subunit alpha,Fc-epsilon RI-alpha,FCER1A,Fc Fragment Of IgE Receptor Ia,Fc Fragment Of IgE, High Affinity I, Receptor For,Alpha Polypeptide,Fc Epsilon Receptor Ia,FcERI,Immunoglobulin E Receptor, High-Affinity, Of Mast Cells, Alpha Polypeptide,High Affinity Immunoglobulin Epsilon Receptor Alpha-Subunit,High Affinity Immunoglobulin Epsilon Receptor Subunit Alpha,Fc IgE Receptor, Alpha Polypeptide,Fc Epsilon RI Alpha-Chain,FCER1
Höchste Forschungs- und EntwicklungsphaseApproved
Englischer NameIgE Fc receptor, alpha-subunit
Target-AliasFc Fragment Of IgE, High Affinity I, Receptor For; Alpha Polypeptide,FCE1A,IgE Fc receptor subunit alpha,Fc-epsilon RI-alpha,FCER1A,Fc Fragment Of IgE Receptor Ia,Fc Fragment Of IgE, High Affinity I, Receptor For,Alpha Polypeptide,Fc Epsilon Receptor Ia,FcERI,Immunoglobulin E Receptor, High-Affinity, Of Mast Cells, Alpha Polypeptide,High Affinity Immunoglobulin Epsilon Receptor Alpha-Subunit,High Affinity Immunoglobulin Epsilon Receptor Subunit Alpha,Fc IgE Receptor, Alpha Polypeptide,Fc Epsilon RI Alpha-Chain,FCER1
Anzahl der inverkehr gebrachten Arzneimittel1
Anzahl der klinischen Arzneimittel1
Höchste Forschungs- und EntwicklungsphaseApproved

Fc epsilon RI alpha Produktliste

  • Attribut

    Protein (6)

  • Produktbibliothek

    Online (6)

  • Spezies

    Human (3)Cynomolgus (2)Mouse (1)

  • Etikett

    His Tag (2)Fc Tag (3)His Tag & Avi Tag (1)

  • Marker

    Unconjugated (5)Biotin-labeled (1)

Fc epsilon RI alpha Molekülhintergrund

Fc epsilon RI alpha (FcεRIα) is the α-chain of the high-affinity IgE receptor (FcεRI), a critical mediator of type I hypersensitivity. As a transmembrane glycoprotein in the immunoglobulin superfamily, its extracellular domain specifically binds the Fc region of IgE. Mainly expressed on mast cells and basophils, FcεRIα cross-linking (by IgE-allergen complexes) triggers cell degranulation, releasing histamine and proinflammatory mediators—driving allergies, asthma, and anaphylaxis. It also participates in immune surveillance. Owing to its central role in allergic responses, FcεRIα is a key therapeutic target for anti-allergy agents.

Fc epsilon RI alpha Molekülalias

FCER1A,FCE1A,FcERI

Klinische Arzneimittelinformation

Englischer NameForschungscodeForschungsphaseFirmaIndikationenKlinische Studie
LesigerceptYH-35324; GI-301Phase 2 ClinicalYuhan CorpChronic Urticaria; Hypersensitivity; Immune System Diseases; Urinary Tract Infections; Urticaria
Details

Inverkehr gebrachte Arzneimittelinformation

Englischer NameForschungscodeForschungsphaseFirmaFrühestes MarkennameFrühestes GenehmigungslandFrüheste IndikationFrüheste GenehmigungsgesellschaftFrüheste GenehmigungsdatumIndikationenKlinische Studie
Benzylpenicilloyl PolylysineApprovedAllerquest LlcPre-penUnited StatesAnaphylaxis; Diagnostic agentsAllerquest Inc1974-07-25Anaphylaxis; Diagnostic agents
Details
  • Molekülinformation
  • Produktliste
  • Inverkehr gebrachte Arzneimittelinformation
  • Klinische Arzneimittelinformation
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