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EpCAM
EpCAM Overview
| English Name | Epithelial cell adhesion molecule | Approved Drugs | 1 |
| Drugs in Clinical Trials | 12 | Target Synonym | Epithelial Cell Adhesion Molecule，Tumor-Associated Calcium Signal Transducer 1，Major Gastrointestinal Tumor-Associated Protein GA733-2，Cell Surface Glycoprotein Trop-1，Epithelial Glycoprotein 314，TROP1，KSA，Membrane Component， Chromosome 4， Surface Marker (35kD Glycoprotein)，Antigen Identified By Monoclonal Antibody AUA1，Human Epithelial Glycoprotein-2，Epithelial Cell Surface Antigen，CD326 Antigen，HEGP314，HNPCC8，Ep-CAM，DIAR5，EGP-2，EGP40，KS1/4，MK-1，M1S2，ESA，Ly74，TACST-1，CO-17A，17-1A，EGP34，HEA125，MH99，MOC31，323/A3，Trophoblast Cell Surface Antigen 1，Adenocarcinoma-associated antigen，EGP314，GA733-2，M4S1，TACSTD1，Epithelial glycoprotein，EGP，KS 1/4 antigen，MIC18，CD326，EPCAM |
| Highest Development Stage | Approved | ||
| English Name | Epithelial cell adhesion molecule |
| Target Synonym | Epithelial Cell Adhesion Molecule，Tumor-Associated Calcium Signal Transducer 1，Major Gastrointestinal Tumor-Associated Protein GA733-2，Cell Surface Glycoprotein Trop-1，Epithelial Glycoprotein 314，TROP1，KSA，Membrane Component， Chromosome 4， Surface Marker (35kD Glycoprotein)，Antigen Identified By Monoclonal Antibody AUA1，Human Epithelial Glycoprotein-2，Epithelial Cell Surface Antigen，CD326 Antigen，HEGP314，HNPCC8，Ep-CAM，DIAR5，EGP-2，EGP40，KS1/4，MK-1，M1S2，ESA，Ly74，TACST-1，CO-17A，17-1A，EGP34，HEA125，MH99，MOC31，323/A3，Trophoblast Cell Surface Antigen 1，Adenocarcinoma-associated antigen，EGP314，GA733-2，M4S1，TACSTD1，Epithelial glycoprotein，EGP，KS 1/4 antigen，MIC18，CD326，EPCAM |
| Approved Drugs | 1 |
| Drugs in Clinical Trials | 12 |
| Highest Development Stage | Approved |
EpCAM Product List
- Product Category
Protein (12)Antibody (1)Cell (1)
- Product Status
Launched (14)
- Species
Human (10)Mouse (1)Rhesus macaque (2)Rabbit (1)
- Tag
Fc Tag (2)His Tag (4)His Tag & Avi Tag (2)Fc Tag & Avi Tag (1)Mouse IgG Fc Tag (1)Llama IgG Fc Tag (1)- (2)Tag Free (1)
- Conjugate
Unconjugated (8)Biotin-labeled (3)FITC Labeled (2)- (1)
| Cat. No. | Species | Host | Product Description | Structure | Purity | Feature |
|---|---|---|---|---|---|---|
HOT EPM-H5223 |  Human | HEK293 | Human EpCAM / TROP1 Protein, His Tag |  |  |  |
HOT EPM-H5254 | Human | HEK293 | Human EpCAM / TROP1 Protein, Fc Tag |  | | |
HOT EPM-H82E8 | Human | HEK293 | Biotinylated Human EpCAM / TROP1 Protein, Avitag™,His Tag (MALS verified) |  | | |
HOT EPM-H82F9 | Human | HEK293 | Biotinylated Human EpCAM / TROP1 Protein, Fc,Avitag™ (MALS verified) |  | | |
HOT EPM-R82E3 |  Rhesus macaque | HEK293 | Biotinylated Rhesus macaque EpCAM / TROP1 Protein, His,Avitag™ (MALS verified) |  | | |
CHEK-ATP175 | Human | HEK293 | HEK293/Human EpCAM Stable Cell Line |  | ||
EPM-H5213 | Human | HEK293 | Human EpCAM / TROP1 Protein, Tag Free (MALS verified) |  | | |
EPM-H5255 | Human | HEK293 | Human EpCAM / TROP1 Protein, Mouse IgG2a Fc Tag |  | | |
EPM-H5259 | Human | HEK293 | Human EpCAM / TROP1 Protein, Llama IgG2b Fc Tag, low endotoxin |  | | |
EPM-HF225 | Human | HEK293 | FITC-Labeled Human EpCAM / TROP1 Protein, His Tag |  | | |
Total: 14
- 1
- 2
EpCAM Synonyms
EPCAM,TACSTD1,TROP1,CD326,DIAR5,EGP2,EGP314,EGP40,ESA,GA733-2,HNPCC8,HNPCC-8,KS1,4,KSA,M4S1,MIC18,MK1
Antibody Project Trading Platform
| Project Name | Project Stage | Molecule Type | Molecule Source | Disease Area | Indication |
|---|---|---|---|---|---|
| EpCAM CAR-T -01 | IIT | CAR | Humanized Mouse | Solid Tumor | Gastric Cancer |
Clinical Drug Information
| English Name | Research Code | Highest Development Stage | Company | Indication | Clinical Trial |
|---|---|---|---|---|---|
| Recombinant Anti-EpCAM and Anti-CD3Human-mouse Chimeric Bispecific Antibody for Injection (Wuhan Yzy Biopharma Co Ltd) | M-701 | Phase 3 Clinical | Wuhan Yzy Biopharma Co Ltd | Ascites; Carcinoma, Non-Small-Cell Lung; Colorectal Neoplasms; Hydrothorax; Neoplasms; Ovarian Neoplasms; Pleural Effusion, Malignant; Solid tumours; Stomach Neoplasms | Details |
| Oportuzumab monatox | 4D5MOCB-ETA; VB4-845; VB-4847; B-4845; VB-845 | Phase 3 Clinical | Sesen Bio Inc, Viventia Biotech Inc | Carcinoma, Squamous Cell; Head and Neck Neoplasms; Mouth Neoplasms; Neoplasms, Squamous Cell; Squamous Cell Carcinoma of Head and Neck; Urinary Bladder Neoplasms | Details |
| Anti-EPCAM CAR-T cell therapy (Sinobioway) | Phase 2 Clinical | Beijing Sinobioway Bioengineering Group Co Ltd | Liver Neoplasms; Stomach Neoplasms | Details | |
| DuoBody-EpCAMx4-1BB | BNT314/GEN1059; GEN-1059; GEN1059; BNT314 | Phase 2 Clinical | Biontech Se, Genmab A/S | Colorectal Neoplasms; Neoplasms; Solid tumours | Details |
| IMC-001(Immunofoco) | IMC001; IMC-001 | Phase 2 Clinical | Suzhou Immunofoco Biotechnology Co Ltd | Biliary Tract Neoplasms; Carcinoma, Hepatocellular; Colorectal Neoplasms; Digestive System Neoplasms; Esophageal Neoplasms; Gastroenteropancreatic neuroendocrine tumor; Gastroesophageal Junction Neoplasms; Gastrointestinal Neoplasms; Ovarian Neoplasms; Pancreatic Neoplasms; Solid tumours; Stomach Neoplasms; Triple Negative Breast Neoplasms | Details |
| BA-3182 | BA-3182 | Phase 1 Clinical | Bioatla | Adenocarcinoma; Solid tumours | Details |
| KK-2269 | KK-2269; KK2269 | Phase 1 Clinical | Kyowa Kirin Inc | Carcinoma, Non-Small-Cell Lung; Esophageal adenocarcinoma; Gastroesophageal Junction Neoplasms; Solid tumours; Stomach Neoplasms | Details |
| AM-928 | AM-928 | Phase 1 Clinical | AcadeMab Biomedical Inc | Colorectal Neoplasms; Head and Neck Neoplasms; Solid tumours; Thyroid Carcinoma, Anaplastic | Details |
| Varsetatug masetecan | CX-2051; Varseta-M | Phase 1 Clinical | Cytomx Therapeutics Inc, Immunogen Inc | Colorectal Neoplasms; Neoplasms; Solid tumours | Details |
| 99mTc-HE3-G3 | 99mTc-HE3-G3; 99-mTc-HE-3-G-3; 99m-Tc-HE-3-G-3; 99mTc-(HE)3-G3; 99mTc-(CO)3-(HE)3-Ec1; [99mTc]Tc(CO)3-(HE)3-Ec1 | Phase 1 Clinical | Tomsk National Research Medical Center Of The Russian Academy Of Sciences | Breast Neoplasms; Solid tumours | Details |
| A-337 | A-337 | Phase 1 Clinical | Evive Biotech Ltd | Neoplasms; Solid tumours | Details |
| PMC2129G12 | PMC2129G12 | Forevertech Biotechnologies Co Ltd | Details |
Marketed Drug Information
| English Name | Research Code | Highest Development Stage | Company | Earliest Brand Name | Earliest Approval Country | Earliest Indication | Earliest Approval Company | Earliest Approval Date | Indication | Clinical Trial |
|---|---|---|---|---|---|---|---|---|---|---|
| Catumaxomab | LP000 | Approved | Neovii Biotech Gmbh, Trion Research | Removab, Korjuny | EU | Ascites | Lindis Biotech GmbH | 2009-04-20 | Ascites; Breast Neoplasms; Carcinoma; Carcinoma, Ovarian Epithelial; Colonic Neoplasms; Neoplasms; Ovarian Neoplasms; Stomach Neoplasms; Urinary Bladder Neoplasms | Details |
Product Reviews
A***O2025-07-30
0People LikeI tested the FITC-EpCAM protein for binding to our anti-EpCAM CAR-T cells which were made by lentiviral transduction of human T cells . The protein stained the CAR-T cells but not the control T cells at both 10 ug/ml and 2 ug/ml. It's a good product.- K***n2023-05-03 1People LikeOverall, we were very pleased with the entire process of buying and using the product—shipping was quick and the product was packaged and stored well. The protein was used in the development of a lateral-flow immunoassay (LFA) to detect for EpCAM. Combinations of anti-EpCAM antibodies were first screened using the product, from which we were able to successfully see strong binding on spot tests in duplicate for certain antibody combination pairs. These tests allowed us to confidently move forward with printing and assembling proper LFAs.
- J***a2021-09-17 0People LikeWe received the product with a fairly fast speed, we used this product for antibody screening and ELISA. The product is robust and good quality.
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- Marketed Drug Information
- Product Reviews
- Clinical Drug Information
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