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EpCAM

EpCAM

EpCAM Overview

Molecule Name
Epithelial cell adhesion molecule
Synonyms
EPCAM,TACSTD1,TROP1,CD326,DIAR5,EGP2,EGP314,EGP40,ESA,GA733-2,HNPCC8,HNPCC-8,KS1,4,KSA,M4S1,MIC18,MK1
Drug Development Progress
Drugs in Clinical Trials12
Approved Drugs1
Highest Development StageApproved
Target Synonym
Epithelial Cell Adhesion Molecule，Tumor-Associated Calcium Signal Transducer 1，Major Gastrointestinal Tumor-Associated Protein GA733-2，Cell Surface Glycoprotein Trop-1，Epithelial Glycoprotein 314，TROP1，KSA，Membrane Component， Chromosome 4， Surface Marker (35kD Glycoprotein)，Antigen Identified By Monoclonal Antibody AUA1，Human Epithelial Glycoprotein-2，Epithelial Cell Surface Antigen，CD326 Antigen，HEGP314，HNPCC8，Ep-CAM，DIAR5，EGP-2，EGP40，KS1/4，MK-1，M1S2，ESA，Ly74，TACST-1，CO-17A，17-1A，EGP34，HEA125，MH99，MOC31，323/A3，Trophoblast Cell Surface Antigen 1，Adenocarcinoma-associated antigen，EGP314，GA733-2，M4S1，TACSTD1，Epithelial glycoprotein，EGP，KS 1/4 antigen，MIC18，CD326，EPCAM

EpCAM Product List

Species
  • Human（9）
  • Rhesus macaque（2）
  • Mouse（1）
Tag
  • His Tag（4）
  • Fc Tag（2）
  • His Tag & Avi Tag（2）
  • Fc Tag & Avi Tag（1）
  • Llama IgG Fc Tag（1）
  • Mouse IgG Fc Tag（1）
  • Tag Free（1）
Host
  • HEK293（12）
Conjugate
  • Unconjugated（7）
  • Biotin-labeled（3）
  • FITC Labeled（2）
Grade
  • RUO（12）
Low Endotoxin
  • Yes（2）
  • No（10）
MoleculeCat. No.Product NameSpeciesHostStructurePurityActivitySize&Price
EpCAM
HOTAvitag
EPM-H82F9
Biotinylated Human EpCAM / TROP1 Protein, Fc,Avitag™ (MALS verified)
Human
HEK293
MALSSDS-PAGE
ELISA

$360.00

25ug
EpCAM
HOT
EPM-H5223
Human EpCAM / TROP1 Protein, His Tag, low endotoxin
Human
HEK293
SDS-PAGE
ELISA

$320.00

100ug
EpCAM
HOTAvitag
EPM-R82E3
Biotinylated Rhesus macaque EpCAM / TROP1 Protein, His,Avitag™ (MALS verified)
Rhesus macaque
HEK293
MALSSDS-PAGE
ELISA

$380.00

25ug
EpCAM
HOT
EPM-H5254
Human EpCAM / TROP1 Protein, Fc Tag
Human
HEK293
SDS-PAGE
ELISA

$310.00

100ug
EpCAM
HOTAvitag
EPM-H82E8
Biotinylated Human EpCAM / TROP1 Protein, Avitag™,His Tag (MALS verified)
Human
HEK293
MALSSDS-PAGE
ELISA

$380.00

25ug
EpCAM
AIDD‑Ready
EPM-C5227
Rhesus macaque EpCAM / TROP1 Protein, His Tag
Rhesus macaque
HEK293
SDS-PAGE
ELISASPR

$380.00

50ug
EpCAM
EPM-H5213
Human EpCAM / TROP1 Protein, Tag Free (MALS verified)
Human
HEK293
MALSSDS-PAGE

$360.00

100ug
EpCAM
EPM-H5255
Human EpCAM / TROP1 Protein, Mouse IgG2a Fc Tag
Human
HEK293
SDS-PAGE
ELISA

$310.00

100ug
EpCAM
EPM-H5259
Human EpCAM / TROP1 Protein, Llama IgG2b Fc Tag, low endotoxin
Human
HEK293
SDS-PAGE
ELISA

$310.00

100ug
EpCAM
EPM-HF225
FITC-Labeled Human EpCAM / TROP1 Protein, His Tag
Human
HEK293
SDS-PAGE
ELISA

$330.00

25ug
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Antibody Project Trading Platform

Project NameProject StageMolecule TypeMolecule SourceDisease AreaIndication
EpCAM CAR-T -01IITCARHumanized MouseSolid TumorGastric Cancer
Project Name
EpCAM CAR-T -01
Project Stage
IIT
Molecule Type
CAR
Molecule Source
Humanized Mouse
Disease Area
Solid Tumor
Indication
Gastric Cancer
Resources

Clinical Drug Information

English NameResearch CodeHighest Development StageCompanyIndicationClinical Trial
Recombinant Anti-EpCAM and Anti-CD3Human-mouse Chimeric Bispecific Antibody for Injection (Wuhan Yzy Biopharma Co Ltd)M-701Phase 3 ClinicalWuhan Yzy Biopharma Co Ltd
Ascites; Carcinoma, Non-Small-Cell Lung; Colorectal Neoplasms; Hydrothorax; Neoplasms; Ovarian Neoplasms; Pleural Effusion, Malignant; Solid tumours; Stomach Neoplasms
Details
Oportuzumab monatox4D5MOCB-ETA; VB4-845; VB-4847; B-4845; VB-845Phase 3 ClinicalSesen Bio Inc, Viventia Biotech Inc
Carcinoma, Squamous Cell; Head and Neck Neoplasms; Mouth Neoplasms; Neoplasms, Squamous Cell; Squamous Cell Carcinoma of Head and Neck; Urinary Bladder Neoplasms
Details
Anti-EPCAM CAR-T cell therapy (Sinobioway)Phase 2 ClinicalBeijing Sinobioway Bioengineering Group Co Ltd
Liver Neoplasms; Stomach Neoplasms
Details
DuoBody-EpCAMx4-1BBBNT314/GEN1059; GEN-1059; GEN1059; BNT314Phase 2 ClinicalBiontech Se, Genmab A/S
Colorectal Neoplasms; Neoplasms; Solid tumours
Details
IMC-001(Immunofoco)IMC001; IMC-001Phase 2 ClinicalSuzhou Immunofoco Biotechnology Co Ltd
Biliary Tract Neoplasms; Carcinoma, Hepatocellular; Colorectal Neoplasms; Digestive System Neoplasms; Esophageal Neoplasms; Gastroenteropancreatic neuroendocrine tumor; Gastroesophageal Junction Neoplasms; Gastrointestinal Neoplasms; Ovarian Neoplasms; Pancreatic Neoplasms; Solid tumours; Stomach Neoplasms; Triple Negative Breast Neoplasms
Details
BA-3182BA-3182Phase 1 ClinicalBioatla
Adenocarcinoma; Solid tumours
Details
KK-2269KK-2269; KK2269Phase 1 ClinicalKyowa Kirin Inc
Carcinoma, Non-Small-Cell Lung; Esophageal adenocarcinoma; Gastroesophageal Junction Neoplasms; Solid tumours; Stomach Neoplasms
Details
AM-928AM-928Phase 1 ClinicalAcadeMab Biomedical Inc
Colorectal Neoplasms; Head and Neck Neoplasms; Solid tumours; Thyroid Carcinoma, Anaplastic
Details
Varsetatug masetecanCX-2051; Varseta-MPhase 1 ClinicalCytomx Therapeutics Inc, Immunogen Inc
Colorectal Neoplasms; Neoplasms; Solid tumours
Details
99mTc-HE3-G399mTc-HE3-G3; 99-mTc-HE-3-G-3; 99m-Tc-HE-3-G-3; 99mTc-(HE)3-G3; 99mTc-(CO)3-(HE)3-Ec1; [99mTc]Tc(CO)3-(HE)3-Ec1Phase 1 ClinicalTomsk National Research Medical Center Of The Russian Academy Of Sciences
Breast Neoplasms; Solid tumours
Details
A-337A-337Phase 1 ClinicalEvive Biotech Ltd
Neoplasms; Solid tumours
Details
PMC2129G12PMC2129G12Forevertech Biotechnologies Co Ltd
Details

Marketed Drug Information

English NameResearch CodeHighest Development StageCompanyFirst Brand NameFirst Approved CountryFirst IndicationFirst Approved CompanyFirst Approved DateIndicationClinical Trial
CatumaxomabLP000ApprovedNeovii Biotech Gmbh, Trion ResearchRemovab, KorjunyEUAscitesLindis Biotech GmbH2009-04-20
Ascites; Breast Neoplasms; Carcinoma; Carcinoma, Ovarian Epithelial; Colonic Neoplasms; Neoplasms; Ovarian Neoplasms; Stomach Neoplasms; Urinary Bladder Neoplasms
Details
Customer Reviews
  • A***O2025-07-30
    FITC-Labeled Human EpCAM / TROP1 Protein, His Tag
    I tested the FITC-EpCAM protein for binding to our anti-EpCAM CAR-T cells which were made by lentiviral transduction of human T cells . The protein stained the CAR-T cells but not the control T cells at both 10 ug/ml and 2 ug/ml. It's a good product.
  • K***n2023-05-03
    Human EpCAM / TROP1 Protein, His Tag, low endotoxin
    Overall, we were very pleased with the entire process of buying and using the product—shipping was quick and the product was packaged and stored well. The protein was used in the development of a lateral-flow immunoassay (LFA) to detect for EpCAM. Combinations of anti-EpCAM antibodies were first screened using the product, from which we were able to successfully see strong binding on spot tests in duplicate for certain antibody combination pairs. These tests allowed us to confidently move forward with printing and assembling proper LFAs.
  • J***a2021-09-17
    Human EpCAM / TROP1 Protein, His Tag, low endotoxin
    We received the product with a fairly fast speed, we used this product for antibody screening and ELISA. The product is robust and good quality.