Human EpCAM / TROP1 Protein, Tag Free (MALS verified)

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Cat. No. / Size
Price
Qty
EPM-H5213-100ug
$360.00
EPM-H5213-1mg
$1565.00
ETA of in-stock products:2 business days

Product Details

  • Synonyms

    EPCAM, TACSTD1, TROP1, CD326, DIAR5, EGP2, EGP314, EGP40, ESA, GA733-2, HNPCC8, HNPCC-8, KS1, 4, KSA, M4S1, MIC18, MK1

  • Source

    Human EpCAM Protein, Tag Free (EPM-H5213) is expressed from human 293 cells (HEK293). It contains AA Gln 24 - Lys 265 (Accession # P16422).

    Predicted N-terminus: Gln 24

    Request for sequence
  • Molecular Characterization

    EpCAM Structure

    Other Tags and Version Biotin & Other Labeled Version

    This protein carries no "tag".

    The protein has a calculated MW of 30.2 kDa. The protein migrates as 35-40 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

  • Endotoxin

    Less than 1.0 EU per μg by the LAL method / rFC method.

  • Purity

    >95% as determined by SDS-PAGE.

    >90% as determined by SEC-MALS.

  • Formulation

    Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • ACRO Quality Management System

    1. QMS(ISO, GMP)
    2. Quality Advantages
    3. Quality Control Process

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Performance Data

  • SDS-PAGE

    EpCAM SDS-PAGE

    Human EpCAM Protein, Tag Free on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95% (With Star Ribbon Pre-stained Protein Marker).

  • SEC-MALS

    EpCAM SEC-MALS

    The purity of Human EpCAM Protein, Tag Free (Cat. No. EPM-H5213) is more than 90% and the molecular weight of this protein is around 25-40 kDa verified by SEC-MALS.

    Report

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Background

This gene encodes a carcinoma-associated antigen and is a member of a family that includes at least two type I membrane proteins. This antigen is expressed on most normal epithelial cells and gastrointestinal carcinomas and functions as a homotypic calcium-independent cell adhesion molecule. The antigen is being used as a target for immunotherapy treatment of human carcinomas. Mutations in this gene result in congenital tufting enteropathy. [provided by RefSeq, Dec 2008]

Recent Advances

 
Drug Development Progress
  • English Name:

    Epithelial cell adhesion molecule

  • Category:

  • Approved Drugs:

    1 Details

  • Drugs in Clinical Trials:

    11 Details

  • Highest Development Stage:

    Approved

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