Complement C2

Complement C2 Molekülinformation

Englischer Name	Complement C2	Anzahl der inverkehr gebrachten Arzneimittel	0
Anzahl der klinischen Arzneimittel	1	Target-Alias	C3/C5 convertase
Höchste Forschungs- und Entwicklungsphase	Phase 3 Clinical

Englischer Name	Complement C2
Target-Alias	C3/C5 convertase
Anzahl der inverkehr gebrachten Arzneimittel	0
Anzahl der klinischen Arzneimittel	1
Höchste Forschungs- und Entwicklungsphase	Phase 3 Clinical

Complement C2 Produktliste

Attribut
Protein (8)
Produktbibliothek
Online (8)
Spezies
Human (1)Cynomolgus (2)Canine (1)Rat (1)Porcine (1)Rabbit (1)Mouse (1)
Etikett
His Tag (3)His Tag & Avi Tag (5)
Marker
Unconjugated (3)Biotin-labeled (5)

Produktnummer	Spezies	Expressionssystem	Produktbeschreibung	Vorbestellen/Bestellen
HOT CO2-H52H7	Human	HEK293	Human Complement C2 Protein, His Tag (MALS verified) (active enzyme)	In den Warenkorb legen
HOT CO2-C52H8	Cynomolgus	HEK293	Cynomolgus Complement C2 Protein, His Tag (active enzyme)	In den Warenkorb legen
HOT CO2-R82E6	Rat	HEK293	Biotinylated Rat Complement C2 Protein, His,Avitag™ (active enzyme)	In den Warenkorb legen
CO2-M52H3	Mouse	HEK293	Mouse Complement C2 Protein, His Tag, low endotoxin (MALS verified)	In den Warenkorb legen
CO2-C82E7	Cynomolgus	HEK293	Biotinylated Cynomolgus Complement C2 Protein, His,Avitag™ (active enzyme, MALS verified)	In den Warenkorb legen
CO2-D82E4	Canine	HEK293	Biotinylated Canine Complement C2 Protein, His,Avitag™ (active enzyme)	In den Warenkorb legen
CO2-D82E5	Porcine	HEK293	Biotinylated Porcine Complement C2 Protein, His,Avitag™ (active enzyme)	In den Warenkorb legen
CO2-R82E3	Rabbit	HEK293	Biotinylated Rabbit Complement C2 Protein, His,Avitag™ (active enzyme)	In den Warenkorb legen

Gesamtmenge8

Complement C2 Molekülhintergrund

C2 is a major histocompatibility complex class-III protein. Component C2 which is part of the classical pathway of the complement system is cleaved by activated factor C1 into two fragments: C2b and C2a. C2a, a serine protease, then combines with complement factor C4b to generate the C3 or C5 convertase. The lectin (LP) and classical (CP) pathways are two of the three main activation cascades of the complement system. These pathways start with recognition of different pathogen- or danger-associated molecular patterns and include identical steps of proteolytic activation of complement component C4, formation of the C3 proconvertase C4b2, followed by cleavage of complement component C2 within C4b2 resulting in the C3 convertase C4b2a.

Complement C2 Molekülalias

C2,Complement C2,Complement Component C2

Klinische Arzneimittelinformation

Englischer Name	Forschungscode	Forschungsphase	Firma	Indikationen	Klinische Studie
Empasiprubart	ARGX-117	Phase 3 Clinical	Argenx Se, Broteio Pharma BV	Coronavirus Disease 2019 (COVID-19); Delayed Graft Function; Dermatomyositis; Motor Neuron Disease; Multifocal Motor Neuropathy; Myasthenia Gravis; Myositis; Polyneuropathies; Polyradiculoneuropathy, Chronic Inflammatory Demyelinating	Details