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CD8 alpha & beta

CD8 alpha & beta Molekülinformation

Englischer NameT-cell surface glycoprotein CD8 beta chainAnzahl der inverkehr gebrachten Arzneimittel0
Anzahl der klinischen Arzneimittel0Target-AliasCD8b,CD8b Molecule
Höchste Forschungs- und EntwicklungsphasePreclinical
Englischer NameT-cell surface glycoprotein CD8 beta chain
Target-AliasCD8b,CD8b Molecule
Anzahl der inverkehr gebrachten Arzneimittel0
Anzahl der klinischen Arzneimittel0
Höchste Forschungs- und EntwicklungsphasePreclinical

CD8 alpha & beta Molekülhintergrund

Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. CD8A forms disulfide-linked heterodimers with CD8B at the cell surface. CD8A homodimer molecules also promote the survival and differentiation of activated lymphocytes into memory CD8 T-cells. Additionally, CD8B plays a critical role in thymic selection of CD8+ T-cells. A palmitoylation site in the cytoplasmic tail of CD8B chain contributes to partitioning of CD8 into the plasma membrane lipid rafts where signaling proteins are enriched.

CD8 alpha & beta Molekülalias

CD8 alpha & beta,CD8A & CD8B
  • Molekülinformation
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