CD133

CD133 Molekülinformation

Englischer Name	CD133	Anzahl der inverkehr gebrachten Arzneimittel	0
Anzahl der klinischen Arzneimittel	2	Target-Alias	Antigen AC133，Prominin-1，PROM1，Prominin 1，Prominin-Like Protein 1，PROML1，Stargardt Disease 4 (Autosomal Dominant)，Hematopoietic Stem Cell Antigen，Macular Dystrophy， Retinal 2，Prominin (Mouse)-Like 1，CD133 Antigen，HProminin，MSTP061，CORD12，AC133，CD133，MCDR2，STGD4，RP41，AC133 Antigen
Höchste Forschungs- und Entwicklungsphase	Phase 2 Clinical

Englischer Name	CD133
Target-Alias	Antigen AC133，Prominin-1，PROM1，Prominin 1，Prominin-Like Protein 1，PROML1，Stargardt Disease 4 (Autosomal Dominant)，Hematopoietic Stem Cell Antigen，Macular Dystrophy， Retinal 2，Prominin (Mouse)-Like 1，CD133 Antigen，HProminin，MSTP061，CORD12，AC133，CD133，MCDR2，STGD4，RP41，AC133 Antigen
Anzahl der inverkehr gebrachten Arzneimittel	0
Anzahl der klinischen Arzneimittel	2
Höchste Forschungs- und Entwicklungsphase	Phase 2 Clinical

CD133 Produktliste

Attribut
Protein (7)Cell (1)
Produktbibliothek
Online (8)
Spezies
Human (7)Cynomolgus (1)
Etikett
His Tag (3)- (3)His Tag & Avi Tag (1)His Tag & Flag Tag (1)
Marker
Unconjugated (4)Biotin-labeled (2)- (1)PE Labeled (1)

Produktnummer	Spezies	Expressionssystem	Produktbeschreibung	Vorbestellen/Bestellen
HOT CD3-H52H1	Human	HEK293	Human CD133 Full Length Protein, His Tag (Nanodisc)	In den Warenkorb legen
HOT CD3-H52P3	Human	HEK293	Human CD133 Full Length Protein (VLP)	In den Warenkorb legen
HOT CD3-C82E3	Cynomolgus	HEK293	Biotinylated Cynomolgus CD133 Full Length Protein, His,Avitag™ (Detergent)	In den Warenkorb legen
CD3-H51D3	Human	E. coli	Human CD133 Full Length Protein, His,Flag Tag (Detergent)	In den Warenkorb legen
CD3-H52H4	Human	HEK293	Human CD133 Protein, His Tag (Detergent)	In den Warenkorb legen
CD3-H82D3	Human	HEK293	Biotinylated Human CD133 Full Length Protein, His,Flag Tag&Avitag™ (Detergent)	In den Warenkorb legen
CD3-HP2H8	Human	HEK293	PE-Labeled Human CD133 Protein, His Tag	In den Warenkorb legen
CHEK-ATP255	Human	HEK293	HEK293/Human CD133 Stable Cell Line	In den Warenkorb legen

Gesamtmenge8

CD133 Molekülhintergrund

Prominin-1 is also known as CD133, Antigen AC133, PROM1, PROML1 and MSTP061. Is used as marker for hematopoietic stem and progenitor cells (HSPC) for somatic stem cell isolation. May play a role in cell differentiation, proliferation and apoptosis . Binds cholesterol in cholesterol-containing plasma membrane microdomains and may play a role in the organization of the apical plasma membrane in epithelial cells. During early retinal development acts as a key regulator of disk morphogenesis. Involved in regulation of MAPK and Akt signaling pathways. In neuroblastoma cells suppresses cell differentiation such as neurite outgrowth in a RET-dependent manner.

CD133 Molekülalias

CD133,PROM1,PROML1,Prominin-1,AC133

Klinische Arzneimittelinformation

Englischer Name	Forschungscode	Forschungsphase	Firma	Indikationen	Klinische Studie
P-134	P-134; P134	Phase 2 Clinical	Tianjin Tasly Pharmaceutical Co Ltd	Glioblastoma	Details
anti-CD133-CAR vector-transduced T cells		Phase 2 Clinical	Pla General Hospital	Brain Neoplasms; Breast Neoplasms; Colorectal Neoplasms; Liver Neoplasms; Ovarian Neoplasms; Pancreatic Neoplasms; Precursor Cell Lymphoblastic Leukemia-Lymphoma	Details