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Product Details
Synonyms
ROR2, NTRKR2
Source
Cynomolgus ROR2 Protein, His Tag (RO2-C52H3) is expressed from human 293 cells (HEK293). It contains AA Glu 34 - Met 402 (Accession # A0A7N9D5U8).
Predicted N-terminus: Glu 34
Request for sequenceMolecular Characterization
Other Tags and Version Biotin & Other Labeled Version
This protein carries a polyhistidine tag at the C-terminus.
The protein has a calculated MW of 43.1 kDa. The protein migrates as 53-58 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Purity
>90% as determined by SDS-PAGE.
>90% as determined by SEC-MALS.
Formulation
Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.
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Reconstitution
Please see Certificate of Analysis for specific instructions.
For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
Storage
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
- -20°C to -70°C for 12 months in lyophilized state;
- -70°C for 3 months under sterile conditions after reconstitution.
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Data Display
SDS-PAGE
Cynomolgus ROR2 Protein, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 90% (With Star Ribbon Pre-stained Protein Marker).
SEC-MALS
The purity of Cynomolgus ROR2 Protein, His Tag (Cat. No. RO2-C52H3) is more than 90% and the molecular weight of this protein is around 45-60 kDa verified by SEC-MALS.
Report
Bioactivity-ELISA
Immobilized Cynomolgus ROR2 Protein, His Tag (Cat. No. RO2-C52H3) at 1 μg/mL (100 μL/well) can bind Anti-ROR2 Antibody, Human IgG1 with a linear range of 0.06-2 ng/mL (QC tested).
Protocol
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Background Introduction
Frontier Progress
Drug Development Progress- English Name：
Tyrosine-protein kinase transmembrane receptor ROR2
- Category：
- Listed Drugs Count：
0 Details
- Clinical Drugs Count：
1 Details
- Highest R&D Stage：
Phase 2 Clinical
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