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Human Prostatic Acid Phosphatase Protein, His Tag, low endotoxin (active enzyme, MALS verified)

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Menge
PRE-H52H3-20ug
$230.00
In Stock - Delivery in 1-2 business days
PRE-H52H3-100ug
$890.00
In Stock - Delivery in 1-2 business days
PRE-H52H3
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Synonyms

Prostatic Acid Phosphatase, ACPP, ACP-3, PAP, 5'-NT, TMPase, TM-PAP

Source

Human Prostatic Acid Phosphatase Protein, His Tag (PRE-H52H3) is expressed from human 293 cells (HEK293). It contains AA Lys 33 - Lys 382 (Accession # P15309-2).

Predicted N-terminus: Lys 33

Molecular Characterization
Other Tags and Version Biotin & Other Labeled Version

This protein carries a polyhistidine tag at the C-terminus.

The protein has a calculated MW of 42.5 kDa. The protein migrates as 45-50 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

The protein is designed as a dimer.

Endotoxin

Less than 0.01 EU per μg by the LAL method / rFC method.

Purity

>90% as determined by SDS-PAGE.

>95% as determined by SEC-MALS.

Formulation

Supplied as 0.2 μm filtered solution in 100 mM NaAC, pH5.0 with glycerol as protectant.

Contact us for customized product form or formulation.

Shipping and Storage

This product is supplied and shipped on dry ice.

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:
  • The product MUST be stored at -70°C or lower upon receipt;
  • -70°C for 3 months under sterile conditions.
ACRO Quality Management System

Background Introduction

Prostatic acid phosphatase also know as acid phosphatase 3 (ACP3), it is a non-specific tyrosine phosphatase that acts as a tumor suppressor of prostate cancer through dephosphorylation of ERBB2 and deactivation of MAPK-mediated signaling. In addition to its tyrosine phosphatase activity has ecto-5'-nucleotidase activity in dorsal root ganglion (DRG) neurons. Generates adenosine from AMP which acts as a pain suppressor.