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Human NPR3 protein, Fc Tag (MALS verified)

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Product Number/Spec
Price
Menge
NP3-H5253-100ug
$365.00
NP3-H5253-1mg
$2280.00
ETA of in-stock products:2 business days
Gesamtanzahl Product Amount$ 0

Product Details

  • Synonyms

    ANP-C, ANPR-C, ANPRC, BOMOS, C5orf23, GUCY2B, NPR-C, NPRC

  • Source

    Human NPR3 protein, Fc Tag (NP3-H5253) is expressed from human 293 cells (HEK293). It contains AA Thr 24 - Glu 481 (Accession # P17342-1).

    Predicted N-terminus: Thr 24

    Request for sequence
  • Molecular Characterization

    NPR3 Structure

    Other Tags and Version Biotin & Other Labeled Version

    This protein carries a human IgG1 Fc tag at the C-terminus.

    The protein has a calculated MW of 77.1 kDa. The protein migrates as 80-95 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

  • Endotoxin

    Less than 1.0 EU per μg by the LAL method / rFC method.

  • Purity

    >90% as determined by SDS-PAGE.

    >90% as determined by SEC-MALS.

  • Formulation

    Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • ACRO Quality Management System

    1. QMS(ISO, GMP)
    2. Quality Advantages
    3. Quality Control Process

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Data Display

  • SDS-PAGE

    NPR3 SDS-PAGE

    Human NPR3 protein, Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 90% (With Star Ribbon Pre-stained Protein Marker).

  • SEC-MALS

    NPR3 SEC-MALS

    The purity of Human NPR3 protein, Fc Tag (Cat. No. NP3-H5253) is more than 90% and the molecular weight of this protein is around 165-205 kDa verified by SEC-MALS.

    Report

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Publish Comment

Background Introduction

This gene encodes one of three natriuretic peptide receptors. Natriutetic peptides are small peptides which regulate blood volume and pressure, pulmonary hypertension, and cardiac function as well as some metabolic and growth processes. The product of this gene encodes a natriuretic peptide receptor responsible for clearing circulating and extracellular natriuretic peptides through endocytosis of the receptor. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Feb 2011]

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