Mouse MMP-2 Protein, Fc Tag (Pro-form, MALS verified)

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MM2-M5253-50ug
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MM2-M5253-1mg
$1,980.00
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MM2-M5253
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Synonyms

MMP2, CLG4, CLG4A, MMP-II, MONA, TBE-1

Source

Mouse MMP-2 Protein, Fc Tag (MM2-M5253) is expressed from human 293 cells (HEK293). It contains AA Ala 30 - Cys 662 (Accession # P33434-1). It needs to be activated by agents such as APMA in vitro to have hydrolytic activity.

Predicted N-terminus: Ala 30

Molecular Characterization

This protein carries a human IgG1 Fc tag at the C-terminus.

The protein has a calculated MW of 97.5 kDa. The protein migrates as 95-110 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

Purity

>95% as determined by SDS-PAGE.

>90% as determined by SEC-MALS.

Formulation

Supplied as 0.2 μm filtered solution in 50 mM Tris, 150 mM NaCl, pH7.5 with glycerol as protectant.

Contact us for customized product form or formulation.

Shipping and Storage

This product is supplied and shipped on dry ice.

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:
  • The product MUST be stored at -70°C or lower upon receipt;
  • -70°C for 3 months under sterile conditions.

Background Introduction

MMP-2 (Matrix Metalloproteinase-2), also known as Gelatinase A, is a key enzyme belonging to the matrix metalloproteinase (MMP) family. MMPs are zinc-dependent endopeptidases primarily responsible for the degradation of components of the extracellular matrix (ECM), such as collagen, gelatin, and fibronectin.