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Product Details
Synonyms
MIS RII, MRII, AMHR2, AMHR, MISR2, AMH type II receptor
Source
Human MIS RII, Fc Tag (MII-H5258) is expressed from human 293 cells (HEK293). It contains AA Pro 18 - Ser 144 (Accession # Q16671-1).
Predicted N-terminus: Pro 18
Request for sequenceMolecular Characterization
Other Tags and Version Biotin & Other Labeled Version
This protein carries a human IgG1 Fc tag at the C-terminus.
The protein has a calculated MW of 40.0 kDa. The protein migrates as 50-55 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin
Less than 1.0 EU per μg by the LAL method / rFC method.
Purity
>95% as determined by SDS-PAGE.
Formulation
Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.
Contact us for customized product form or formulation.
Reconstitution
Please see Certificate of Analysis for specific instructions.
For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
Shipping and Storage
This product is shipped at ambient temperature.
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
- -20°C to -70°C for 12 months in lyophilized state;
- -70°C for 3 months under sterile conditions after reconstitution.
ACRO Quality Management System
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Data Display
SDS-PAGE
Human MIS RII, Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95% (With Star Ribbon Pre-stained Protein Marker).
User Reviews Publish Comment
K***n2025-04-29
LikesWe purchased this protein and validated its binding to its natural ligand, MIS. We saw great binding between the hMISRII-hFc and MIS ligand, which was exactly what we expected. Additionally, this protein passed our QC requirements for purity on SDS-PAGE and SEC. This was purchased along with several other MISRII products from other companies and this was the only material that bound MIS with expected affinity. As such, we plan to use this protein for our downstream applications.
Background Introduction
Frontier Progress
Drug Development Progress- English Name：
Anti-Mullerian hormone receptor II
- Category：
- Listed Drugs Count：
0 Details
- Clinical Drugs Count：
1 Details
- Highest R&D Stage：
Preclinical
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