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Product Details
Synonyms
Integrin alpha V beta 1, ITGAV&ITGB1
Source
Mouse ITGAV&ITGB1 Heterodimer Protein, Flag Tag&Tag Free (IT1-M53D3) is expressed from CHO cells. It contains AA Phe 31 - Val 988 (ITGAV) & Gln 21 - Asp 728 (ITGB1) (Accession # NP_032428.2 (ITGAV) & NP_034708.1 (ITGB1)).
Predicted N-terminus: Phe 31 (ITGAV) & Gln 21 (ITGB1)
Request for sequenceMolecular Characterization
Other Tags and Version Biotin & Other Labeled Version
Mouse ITGAV&ITGB1 Heterodimer Protein, Flag Tag&Tag Free, produced by co-expression of ITGAV and ITGB1, has a calculated MW of 112.3 kDa (ITGAV) & 83.5 kDa (ITGB1). Subunit ITGAV is fused with flag tag at the C-terminus and subunit ITGB1 contains no tag. The protein migrates as 160-180 kDa (ITGAV) and 120-140 kDa (ITGB1) when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin
Less than 1.0 EU per μg by the LAL method / rFC method.
Purity
>90% as determined by SDS-PAGE.
Formulation
Lyophilized from 0.22 μm filtered solution in 50 mM Tris, 150 mM NaCl, pH8.0 with trehalose as protectant.
Contact us for customized product form or formulation.
Reconstitution
Please see Certificate of Analysis for specific instructions.
For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
Storage
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
- -20°C to -70°C for 12 months in lyophilized state;
- -70°C for 3 months under sterile conditions after reconstitution.
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Data Display
SDS-PAGE
Mouse ITGAV&ITGB1 Heterodimer Protein, Flag Tag&Tag Free on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 90% (With Star Ribbon Pre-stained Protein Marker).
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Background Introduction
Frontier Progress
Drug Development Progress- English Name：
Integrin alpha-V/beta-1
- Category：
- Listed Drugs Count：
0 Details
- Clinical Drugs Count：
5 Details
- Highest R&D Stage：
Phase 2 Clinical
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