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Human IL-9 Protein, His Tag (MALS verified)

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Product Number/Spec
Price
Menge
IL9-H52H9-100ug
$360.00
IL9-H52H9-1mg (500ug X 2)
$2380.00
ETA of in-stock products:2 business days
Gesamtanzahl Product Amount$ 0

Product Details

  • Synonyms

    Interleukin-9, IL-9, Cytokine P40

  • Source

    Human IL-9 Protein, His Tag (IL9-H52H9) is expressed from human 293 cells (HEK293). It contains AA Gln 19 - Ile 144 (Accession # P15248-1).

    Predicted N-terminus: Gln 19

    Request for sequence
  • Molecular Characterization

    IL-9 Structure

    Other Tags and Version Biotin & Other Labeled Version

    This protein carries a polyhistidine tag at the C-terminus.

    The protein has a calculated MW of 16.0 kDa. The protein migrates as 28-37 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

  • Endotoxin

    Less than 0.1 EU per μg by the LAL method / rFC method.

  • Sterility

    Negative

  • Mycoplasma

    Negative

  • Purity

    >90% as determined by SDS-PAGE.

    >95% as determined by SEC-MALS.

  • Formulation

    Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Shipping and Storage

    This product is shipped at ambient temperature.

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • ACRO Quality Management System

    1. QMS(ISO, GMP)
    2. Quality Advantages
    3. Quality Control Process

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Data Display

  • SDS-PAGE

    IL-9 SDS-PAGE

    Human IL-9 Protein, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 90% (With Star Ribbon Pre-stained Protein Marker).

  • SEC-MALS

    IL-9 SEC-MALS

    The purity of Human IL-9 Protein, His Tag (Cat. No. IL9-H52H9) is more than 95% and the molecular weight of this protein is around 23-33 kDa verified by SEC-MALS.

    Report
  • Bioactivity-ELISA

     IL-9 ELISA

    Immobilized Human IL-9 Protein, His Tag (Cat. No. IL9-H52H9) at 5 μg/mL (100 μL/well) can bind Human IL-9R, Fc Tag (Cat. No. ILR-H5251) with a linear range of 5-78 ng/mL (QC tested).

    Protocol

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Publish Comment

Background Introduction

Interleukin-9 (IL-9) is expressed primarily by activated T cells. The growth factor and anti apoptotic activities of IL-9 on multiple transformed cells suggest a potential role for the cytokine in tumourigenesis. IL-9 has also been proposed as a candidate gene for asthma. IL-9 is a Th2-derived cytokine that has been reported to regulate T and B cell function. IL-9 was first isolated as a factor capable of sustaining the long-term growth of murine T cell clones, but has since been demonstrated to have in vitro activities on mast cells, erythroid progenitors, and B cell Ig expression.

Frontier Progress

 
Drug Development Progress
  • English Name:

    Interleukin-9

  • Category:

  • Listed Drugs Count:

    0 Details

  • Clinical Drugs Count:

    1 Details

  • Highest R&D Stage:

    Phase 2 Clinical

Drug Candidate Licensing
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