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Mouse IL-18 R1 / CD218a Protein, His Tag, low endotoxin (MALS & SPR verified)

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IL1-M52H4-200ug
$300.00
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IL1-M52H4-1mg (500ug X 2)
$1,110.00
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IL1-M52H4
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Product Details
Performance Data
Reviews & Citations
Resources
  • Product Details
  • Performance Data
  • Reviews & Citations
  • Important Statement
  • Resources
Synonyms

IL18R1, IL1RRP, CD218a, IL18Ra

Source

Mouse IL-18 R1 Protein, His Tag (IL1-M52H4) is expressed from human 293 cells (HEK293). It contains AA Lys 20 - Gly 326 (Accession # Q61098).

Predicted N-terminus: Lys 20

Molecular Characterization
Other Tags and Version Biotin & Other Labeled Version

This protein carries a polyhistidine tag at the C-terminus.

The protein has a calculated MW of 37.2 kDa. The protein migrates as 55-75 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

Endotoxin

Less than 0.01 EU per μg by the LAL method / rFC method.

Purity

>95% as determined by SDS-PAGE.

>95% as determined by SEC-MALS.

Formulation

Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

Contact us for customized product form or formulation.

Reconstitution

Please see Certificate of Analysis for specific instructions.

For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

Shipping and Storage

This product is shipped at ambient temperature.

For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:
  • -20°C to -70°C for 12 months in lyophilized state;
  • -70°C for 3 months under sterile conditions after reconstitution.
ACRO Quality Management System

Background

Interleukin-18 receptor 1 (IL-18R1), also known as CD218 alpha (CD218a, formerly CDw218a), IL-1 receptor-related protein (IL-1Rrp), and IL-18R alpha, belongs to the interleukin-1 receptor superfamily. IL-18R1 contains three Ig-like C2-type (immunoglobulin-like) domains and one TIR domain. It is a receptor for interleukin-18 (IL-18). Binding of IL-18 to IL-18R1 leads to the activation of NF-κB. IL-18R1 does not bind IL-1 alpha (interleukin-1 alpha) or IL-1 beta (interleukin-1 beta).