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Human GPT (1-496) protein, His Tag

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Menge
GPT-H51H3-50ug
$620.00
In Stock - Delivery in 1-2 business days
GPT-H51H3-500ug
$4,325.00
In Stock - Delivery in 1-2 business days
GPT-H51H3
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Synonyms

AAT1, ALT, ALT1, GPT1, SGPT

Source

Human GPT (1-496) protein, His Tag (GPT-H51H3) is expressed from E. coli cells. It contains AA Met 1 - Ser 496 (Accession # P24298).

Predicted N-terminus: Met 1

Molecular Characterization
Other Tags and Version Biotin & Other Labeled Version

This protein carries a polyhistidine tag at the C-terminus.

The protein has a calculated MW of 56.5 kDa. The protein migrates as 55-60 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE).

Purity

>85% as determined by SDS-PAGE.

Formulation

Supplied as 0.2 μm filtered solution in 20 mM Tris, 0.5 M Arginine, 0.5 M NaCl, pH8.0 with glycerol as protectant.

Contact us for customized product form or formulation.

Shipping and Storage

This product is supplied and shipped on dry ice.

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:
  • The product MUST be stored at -70°C or lower upon receipt;
  • -70°C for 3 months under sterile conditions.
ACRO Quality Management System

Background Introduction

This gene encodes cytosolic alanine aminotransaminase 1 (ALT1); also known as glutamate-pyruvate transaminase 1. This enzyme catalyzes the reversible transamination between alanine and 2-oxoglutarate to generate pyruvate and glutamate and, therefore, plays a key role in the intermediary metabolism of glucose and amino acids. Serum activity levels of this enzyme are routinely used as a biomarker of liver injury caused by drug toxicity, infection, alcohol, and steatosis. A