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Aspergillus fumigatus Dihydroorotate Dehydrogenase Protein, His Tag

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DDE-A51H3-200ug
$1,150.00
In Stock - Delivery in 1-2 business days
DDE-A51H3-1mg
$3,550.00
In Stock - Delivery in 2-3 weeks
DDE-A51H3
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Product Details
Performance Data
Reviews & Citations
Resources
  • Product Details
  • Performance Data
  • Reviews & Citations
  • Important Statement
  • Resources
Synonyms

Dihydroorotate Dehydrogenase

Source

Aspergillus fumigatus Dihydroorotate Dehydrogenase Protein, His Tag (DDE-A51H3) is expressed from E. coli cells. It contains AA Ala 89 - Gln 531 (Accession # A0A229W7A4).

Predicted N-terminus: Met

Molecular Characterization
Other Tags and Version Biotin & Other Labeled Version

This protein carries a polyhistidine tag at the C-terminus.

The protein has a calculated MW of 49.5 kDa. The protein migrates as 55 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE).

Purity

>90% as determined by SDS-PAGE.

Formulation

Supplied as 0.2 μm filtered solution in 50 mM Tris, 150 mM NaCl, pH8.0 with glycerol as protectant.

Contact us for customized product form or formulation.

Shipping and Storage

This product is supplied and shipped on dry ice.

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:
  • The product MUST be stored at -70°C or lower upon receipt;
  • -70°C for 3 months under sterile conditions.
ACRO Quality Management System

Background

Aspergillus fumigatus dihydroorotate dehydrogenase (DHODH) is an essential mitochondrial enzyme in the de novo pyrimidine biosynthesis pathway, required for fungal DNA and RNA synthesis. Because A. fumigatus relies on DHODH for growth and survival, the enzyme has emerged as a validated antifungal drug target, exemplified by inhibitors such as olorofim