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Rhesus macaque B7-H5 / Gi24 / VISTA Protein, His Tag

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Product Number/Spec
Price
Menge
B75-C5220-100ug
$325.00
B75-C5220-1mg
$2155.00
ETA of in-stock products:2 business days
Gesamtanzahl Product Amount$ 0

Product Details

  • Synonyms

    B7-H5, SISP1, Gi24, VISTA

  • Source

    Rhesus macaque B7-H5, His Tag (B75-C5220) is expressed from human 293 cells (HEK293). It contains AA Phe 33 - Thr 192 (Accession # F7F6S6-1).

    Predicted N-terminus: Phe 33

    Request for sequence
  • Molecular Characterization

    B7-H5 Structure

    Other Tags and Version Biotin & Other Labeled Version

    This protein carries a polyhistidine tag at the C-terminus.

    The protein has a calculated MW of 19.9 kDa. The protein migrates as 35-45 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

  • Endotoxin

    Less than 1.0 EU per μg by the LAL method / rFC method.

  • Purity

    >95% as determined by SDS-PAGE.

  • Formulation

    Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • ACRO Quality Management System

    1. QMS(ISO, GMP)
    2. Quality Advantages
    3. Quality Control Process

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Data Display

  • SDS-PAGE

    B7-H5 SDS-PAGE

    Rhesus macaque B7-H5, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95% (With Star Ribbon Pre-stained Protein Marker).

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Publish Comment

Background Introduction

Platelet receptor Gi24, also known as B7-H5 and stress-induced secreted protein-1 (Sisp-1), is a protein that in humans is encoded by the C10orf54 gene, which contains 1 Ig-like (immunoglobulin-like) domain. As for C10orf54 gene, C10orf54 appears to positively interact with BMP-4, potentiating BMP signaling and the transition from an undifferentiated to a differentiated state on ESCs. Human C10orf54 undergoes proteolytic cleavage by MT1-MMP, generating a soluble 30 kDa extracellular fragment plus a 25-30 kDa membrane-bound fragment.

Frontier Progress

 
Drug Development Progress
  • English Name:

    V-domain Ig suppressor of T-cell activation

  • Category:

  • Listed Drugs Count:

    0 Details

  • Clinical Drugs Count:

    8 Details

  • Highest R&D Stage:

    Phase 3 Clinical

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