VSIG4

VSIG4 Molekülinformation

Englischer Name	V-set and immunoglobulin domain-containing protein 4	Anzahl der inverkehr gebrachten Arzneimittel	0
Anzahl der klinischen Arzneimittel	1	Target-Alias	Protein Z39Ig，CRIg，Z39IG
Höchste Forschungs- und Entwicklungsphase	Phase 1 Clinical

Englischer Name	V-set and immunoglobulin domain-containing protein 4
Target-Alias	Protein Z39Ig，CRIg，Z39IG
Anzahl der inverkehr gebrachten Arzneimittel	0
Anzahl der klinischen Arzneimittel	1
Höchste Forschungs- und Entwicklungsphase	Phase 1 Clinical

VSIG4 Produktliste

Attribut
Protein (2)
Produktbibliothek
Online (2)
Spezies
Human (2)
Etikett
His Tag (1)His Tag & Avi Tag (1)
Marker
Unconjugated (1)Biotin-labeled (1)

Produktnummer	Spezies	Expressionssystem	Produktbeschreibung	Proteinstruktur	Reinheit	Eigenschaften	Vorbestellen/Bestellen
VS4-H5226	Human	HEK293	Human VSIG4 Protein, His Tag				In den Warenkorb legen
VS4-H82E3	Human	HEK293	Biotinylated Human VSIG4 Protein, His,Avitag™ (MALS verified)				In den Warenkorb legen

Gesamtmenge2

VSIG4 Molekülhintergrund

V-set and immunoglobulin domain-containing protein 4 (VSIG4) is also known as Protein Z39Ig, is a type I transmembrane glycoprotein. VSIG4 is a B7 family-related protein and an Ig superfamily member. VSIG4 contains two Ig-like (immunoglobulin-like) domains. VSIG4 is abundantly expressed in several fetal tissues. In adult tissues, the highest expression of VSIG4 is in lung and placenta. VSIG4 functions as a negative regulator of T cell activation, and may be involved in the maintenance of peripheral T cell tolerance, and is also identified as a potent suppressor of established inflammation. VSIG4 is a phagocytic receptor, strong negative regulator of T-cell proliferation and IL2 production.