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TRBC1

TRBC1 Molekülinformation

Englischer NameTRBC1Anzahl der inverkehr gebrachten Arzneimittel0
Anzahl der klinischen Arzneimittel4Target-AliasT cell receptor beta constant 1,TRBC1,V_segment Translation Product,BV05S1J2.2,TCRBC1,TCRB
Höchste Forschungs- und EntwicklungsphasePhase 2 Clinical
Englischer NameTRBC1
Target-AliasT cell receptor beta constant 1,TRBC1,V_segment Translation Product,BV05S1J2.2,TCRBC1,TCRB
Anzahl der inverkehr gebrachten Arzneimittel0
Anzahl der klinischen Arzneimittel4
Höchste Forschungs- und EntwicklungsphasePhase 2 Clinical

TRBC1 Produktliste

  • Attribut

    Protein (2)

  • Produktbibliothek

    Online (2)

  • Spezies

    Human (2)

  • Etikett

    His Tag (1)His Tag & Avi Tag (1)

  • Marker

    Unconjugated (1)Biotin-labeled (1)

ProduktnummerSpeziesExpressionssystemProduktbeschreibungProteinstrukturReinheitEigenschaftenVorbestellen/Bestellen
TR1-H52H4
Human
HEK293
Human TRBC1 Protein, His Tag (HPLC verified)
In den Warenkorb legen
TR1-H82E6
Human
HEK293
Biotinylated Human TRBC1 Protein, His,Avitag™
In den Warenkorb legen
Gesamtmenge2
  • 1

TRBC1 Molekülhintergrund

The transmembrane protein, TCR, comprise of two disulphide-linked polypeptide chains: a α and β chain, a γ and δ chain. Each polypeptide chain consists of a variable and a constant region. TRBC1 is the constant region of T-cell receptor (TCR) beta chain. TRBC1 is presented on the surface of T cell and recognized peptide-major histocompatibility (MH) (pMH) that are displayed by antigen presenting cells (APC). TRBC1 is participate in an adaptive immune response and has been well-studied in T cell therapy.

TRBC1 Molekülalias

T cell receptor beta constant 1,TRBC1

Klinische Arzneimittelinformation

Englischer NameForschungscodeForschungsphaseFirmaIndikationenKlinische Studie
Invikafusp AlfaSTAR0602; STAR-0602Phase 2 ClinicalMarengo Therapeutics IncAbdominal Neoplasms; Breast Neoplasms; Carcinoma; Epstein-Barr Virus Infections; Lung Neoplasms; Neoplasms; Papillomavirus Infections; Solid tumours; Triple Negative Breast Neoplasms; Urogenital Neoplasms; Vulvar Diseases; Vulvar Neoplasms
Details
TRBC1/2-Targeted CAR-T Cell Therapy (Second Affiliated Hospital School Of Zhejiang University School Of Medicine)Phase 1 ClinicalSecond Affiliated Hospital School Of Zhejiang University School Of MedicineLymphoma, T-Cell, Peripheral
Details
Anti-TRBC1 CAR-T cell therapy (Shanghai General Hospital)Phase 1 ClinicalShanghai General HospitalHematologic Neoplasms
Details
FT-819FT-8198; FT-819; FT 8198Phase 1 ClinicalMemorial Sloan Kettering Cancer CenterLeukemia, Lymphocytic, Chronic, B-Cell; Lupus Erythematosus, Systemic; Lymphoma, B-Cell; Myositis; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Scleroderma, Systemic
Details

Produktrezensionen

  • 1***82022-08-03
    0Menschen mögen
    The TRBC1 protein is really helpful! Recently, our experiment has not been smooth UNTIL we used the TRBC1 protein and then things finally started to come together! It turns out we were not using the right protein which stopped us from continuing our project. Thank you so much!
  • Molekülinformation
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  • Produktrezensionen
  • Klinische Arzneimittelinformation
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