TDP-43

TDP-43 Molekülinformation

Englischer Name	TAR DNA binding protein 43	Anzahl der inverkehr gebrachten Arzneimittel	0
Anzahl der klinischen Arzneimittel	6	Target-Alias	TAR DNA-binding protein 43，TARDBP，TAR DNA Binding Protein，TDP43，TAR DNA-Binding Protein-43，ALS10
Höchste Forschungs- und Entwicklungsphase	Phase 3 Clinical

Englischer Name	TAR DNA binding protein 43
Target-Alias	TAR DNA-binding protein 43，TARDBP，TAR DNA Binding Protein，TDP43，TAR DNA-Binding Protein-43，ALS10
Anzahl der inverkehr gebrachten Arzneimittel	0
Anzahl der klinischen Arzneimittel	6
Höchste Forschungs- und Entwicklungsphase	Phase 3 Clinical

TDP-43 Produktliste

Attribut
Protein (1)
Produktbibliothek
Online (1)
Spezies
Human (1)
Etikett
His Tag (1)
Marker
Unconjugated (1)

Produktnummer	Spezies	Expressionssystem	Produktbeschreibung	Proteinstruktur	Reinheit	Eigenschaften	Vorbestellen/Bestellen
AIDD‑Ready TD3-H5145	Human	E. coli	Human TDP-43 Protein, His Tag				In den Warenkorb legen

Gesamtmenge1

Produktanfrage

TDP-43 Molekülhintergrund

TDP-43, the transactive response (TAR)-DNA binding Protein with a molecular weight of 43 KDa is encoded by TARDBP gene that located at the chromosome 1. It is a RNA/DNA binding protein that structurally resembles a typical hnRNP protein family member. involved in transcriptional regulation and RNA processing. It is linked to sporadic and familial amyotrophic lateral sclerosis and frontotemporal lobar degeneration. TDP-43 is predominantly nuclear, but it translocates to the cytoplasm under pathological conditions. Cytoplasmic accumulation, phosphorylation, ubiquitination and truncation of TDP-43 are the main hallmarks of TDP-43 proteinopathies.

TDP-43 Molekülalias

TAR DNA-binding protein 43

Klinische Arzneimittelinformation

Englischer Name	Forschungscode	Forschungsphase	Firma	Indikationen	Klinische Studie
Monepantel	PPL-1; NUZ-001	Phase 3 Clinical	Pitney Pharmaceuticals Pty Ltd	Amyotrophic Lateral Sclerosis; Motor Neuron Disease; Neoplasms	Details
nL-TARD-001	nL-TARD-001	Phase 2 Clinical	N-Lorem Foundation	Amyotrophic Lateral Sclerosis	Details
AMDX-2011P	AMDX2011P; AMDX-2011P	Phase 2 Clinical	Amydis Inc	Alzheimer Disease; Amyotrophic Lateral Sclerosis; Cerebral Amyloid Angiopathy; Glaucoma, Open-Angle; Parkinson Disease	Details
VTx-002 (VectorY)	VTx-002	Phase 2 Clinical	VectorY BV	Amyotrophic Lateral Sclerosis	Details
CTx-1000	CTx1000; CTx-1000	Phase 1 Clinical	Celosia Therapeutics Pty Ltd	Amyotrophic Lateral Sclerosis	Details
AB-14	AB-14	Phase 1 Clinical	Autotac Bio Inc	Amyotrophic Lateral Sclerosis	Details

Produktrezensionen

n***l2026-04-14
0Menschen mögen
Human TDP-43 Protein, His Tag
We ordered Human TDP-43 Protein, His Tag and was very happy with the fast shipping to get our project going. Customer service was very helpful on the phone before I placed my order online.