Syndecan-1

Syndecan-1 Molekülinformation

Englischer Name	Syndecan-1	Anzahl der inverkehr gebrachten Arzneimittel	0
Anzahl der klinischen Arzneimittel	2	Target-Alias	Syndecan Proteoglycan 1，CD138 Antigen，SYND1，SDC，Heparan Sulfate Proteoglycan Fibroblast Growth Factor Receptor，Syndecan，CD138，Syndecan-1，SDC1，Syndecan 1
Höchste Forschungs- und Entwicklungsphase	Phase 1 Clinical

Englischer Name	Syndecan-1
Target-Alias	Syndecan Proteoglycan 1，CD138 Antigen，SYND1，SDC，Heparan Sulfate Proteoglycan Fibroblast Growth Factor Receptor，Syndecan，CD138，Syndecan-1，SDC1，Syndecan 1
Anzahl der inverkehr gebrachten Arzneimittel	0
Anzahl der klinischen Arzneimittel	2
Höchste Forschungs- und Entwicklungsphase	Phase 1 Clinical

Syndecan-1 Produktliste

Attribut
Protein (5)
Produktbibliothek
Online (5)
Spezies
Human (5)
Etikett
His Tag & Avi Tag (1)Fc Tag & Avi Tag (1)Fc Tag (1)His Tag (2)
Marker
Biotin-labeled (2)Unconjugated (2)FITC Labeled (1)

Produktnummer	Spezies	Expressionssystem	Produktbeschreibung	Vorbestellen/Bestellen
HOT SY1-H5225	Human	HEK293	Human Syndecan-1 Protein, His Tag	In den Warenkorb legen
HOT SY1-H5253	Human	HEK293	Human Syndecan-1 Protein, Fc Tag	In den Warenkorb legen
HOT SY1-H82E2	Human	HEK293	Biotinylated Human Syndecan-1 Protein, His,Avitag™	In den Warenkorb legen
HOT SY1-H82F3	Human	HEK293	Biotinylated Human Syndecan-1 Protein, Fc,Avitag™	In den Warenkorb legen
SD1-HF228	Human	HEK293	FITC-Labeled Human Syndecan-1 Protein, His Tag	In den Warenkorb legen

Gesamtmenge5

Syndecan-1 Molekülhintergrund

Syndecan-1 (SYND1 or SDC1) is also known as CD antigen CD138, is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-1 / SDC1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. It is a useful marker for plasma cells, but only if the cells tested are already known to be derived from blood.

Syndecan-1 Molekülalias

SDC1,Syndecan-1,CD138,SYND1,SDC

Klinische Arzneimittelinformation

Englischer Name	Forschungscode	Forschungsphase	Firma	Indikationen	Klinische Studie
ATLCAR.CD138 (UNC Lineberger Comprehensive Cancer Center)		Phase 1 Clinical	Unc Lineberger Comprehensive Cancer Center	Immune System Diseases; Multiple Myeloma	Details
QXL-138AM	QXL-138AM	Phase 1 Clinical	Nammi Therapeutics Inc	Breast Neoplasms; Carcinoma, Hepatocellular; Carcinoma, Renal Cell; Carcinoma, Transitional Cell; Gastrointestinal Neoplasms; Lung Neoplasms; Multiple Myeloma; Ovarian Neoplasms; Pancreatic Neoplasms; Prostatic Neoplasms; Solid tumours	Details