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SLC1A2

SLC1A2 Molekülinformation

Englischer NameExcitatory amino acid transporter 2Anzahl der inverkehr gebrachten Arzneimittel0
Anzahl der klinischen Arzneimittel2Target-AliasGLT1,Glutamate/aspartate transporter II,Sodium-dependent glutamate/aspartate transporter 2,Solute carrier family 1 member 2,SLC1A2,EAAT2
Höchste Forschungs- und EntwicklungsphasePhase 2 Clinical
Englischer NameExcitatory amino acid transporter 2
Target-AliasGLT1,Glutamate/aspartate transporter II,Sodium-dependent glutamate/aspartate transporter 2,Solute carrier family 1 member 2,SLC1A2,EAAT2
Anzahl der inverkehr gebrachten Arzneimittel0
Anzahl der klinischen Arzneimittel2
Höchste Forschungs- und EntwicklungsphasePhase 2 Clinical

SLC1A2 Produktliste

  • Attribut

    Protein (1)

  • Produktbibliothek

    Online (1)

  • Spezies

    Human (1)

  • Etikett

    His Tag & Flag Tag (1)

  • Marker

    Unconjugated (1)

ProduktnummerSpeziesExpressionssystemProduktbeschreibungProteinstrukturReinheitEigenschaftenVorbestellen/Bestellen
SL2-H52D6
Human
HEK293
Human SLC1A2 Protein, Flag,His Tag (Detergent)
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Gesamtmenge1
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SLC1A2 Molekülhintergrund

This gene encodes a member of a family of solute transporter proteins. The membrane-bound protein is the principal transporter that clears the excitatory neurotransmitter glutamate from the extracellular space at synapses in the central nervous system. Glutamate clearance is necessary for proper synaptic activation and to prevent neuronal damage from excessive activation of glutamate receptors. Improper regulation of this gene is thought to be associated with several neurological disorders. Alternatively spliced transcript variants of this gene have been identified. [provided by RefSeq, Jun 2017]

SLC1A2 Molekülalias

DEE41, EAAT2, EIEE41, GLT-1, GLT1, HBGT

Klinische Arzneimittelinformation

Englischer NameForschungscodeForschungsphaseFirmaIndikationenKlinische Studie
[18F]RP-115[18F]RP-115Phase 2 ClinicalRio pharmaceuticals IncAlzheimer Disease; Dementia; Frontotemporal Dementia
Details
iQ-007iQ-007Phase 1 ClinicaliQure Pharma IncDrug Resistant Epilepsy; Epilepsies, Partial; Epilepsy; Neuralgia
Details

Produktrezensionen

  • E***a2026-04-29
    0Menschen mögen
    We used this a POC and it worked in some assays where we got informative data. It is great to see detergent-stabilized proteins becoming more available commercially.
  • Molekülinformation
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  • Produktrezensionen
  • Klinische Arzneimittelinformation
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