Siglec-7

Siglec-7 Molekülinformation

Englischer NameSialic acid-binding Ig-like lectin 7Anzahl der inverkehr gebrachten Arzneimittel0
Anzahl der klinischen Arzneimittel0Target-AliasCDw328,AIRM-1,Adhesion inhibitory receptor molecule 1,D-siglec,QA79 membrane protein,CD328
Höchste Forschungs- und EntwicklungsphasePreclinical
Englischer NameSialic acid-binding Ig-like lectin 7
Target-AliasCDw328,AIRM-1,Adhesion inhibitory receptor molecule 1,D-siglec,QA79 membrane protein,CD328
Anzahl der inverkehr gebrachten Arzneimittel0
Anzahl der klinischen Arzneimittel0
Höchste Forschungs- und EntwicklungsphasePreclinical

Siglec-7 Produktliste

  • Attribut

    Protein (4)

  • Produktbibliothek

    Online (4)

  • Spezies

    Human (4)

  • Etikett

    His Tag (1)His Tag & Avi Tag (1)Fc Tag (2)

  • Marker

    Unconjugated (3)Biotin-labeled (1)

Siglec-7 Molekülhintergrund

Siglec-7 is a member of the human CD33‐related Siglec receptor. The extracellular region of Siglec‐7 is characterized by an N‐terminal V‐set Ig domain that can bind sialic acid and two C2‐set Ig domains. The cytoplasmic tail of Siglec‐7 has one immune‐receptor tyrosine‐based inhibitory motif (ITIM) and one ITIM‐like motif. Siglec-7 is considered as a sialic acid-dependent immunoreceptor with inhibitory potential and expressed predominantly on human NK cells, monocytes and a small subset of CD8+ T cells.

Siglec-7 Molekülalias

CDw328,D-siglec,A79 membrane protein,p75,Adhesion inhibitory receptor molecule 1, AIRM-1
  • Molekülinformation
  • Produktliste