Serpin F1

Serpin F1 Molekülinformation

Englischer Name	Pigment epithelium-derived factor	Anzahl der inverkehr gebrachten Arzneimittel	0
Anzahl der klinischen Arzneimittel	2	Target-Alias	Cell proliferation-inducing gene 35 protein，EPC-1，Serpin Family F Member 1，Proliferation-Inducing Protein 35，OI12，Serpin Peptidase Inhibitor， Clade F (Alpha-2 Antiplasmin， Pigment Epithelium Derived Factor)， Member 1，PIG35，Serine (Or Cysteine) Proteinase Inhibitor， Clade F (Alpha-2 Antiplasmin， Pigment Epithelium Derived Factor)， Member 1，OI6，Testis Tissue Sperm-Binding Protein Li 70n，SERPINF1，Serpin F1
Höchste Forschungs- und Entwicklungsphase	Phase 3 Clinical

Englischer Name	Pigment epithelium-derived factor
Target-Alias	Cell proliferation-inducing gene 35 protein，EPC-1，Serpin Family F Member 1，Proliferation-Inducing Protein 35，OI12，Serpin Peptidase Inhibitor， Clade F (Alpha-2 Antiplasmin， Pigment Epithelium Derived Factor)， Member 1，PIG35，Serine (Or Cysteine) Proteinase Inhibitor， Clade F (Alpha-2 Antiplasmin， Pigment Epithelium Derived Factor)， Member 1，OI6，Testis Tissue Sperm-Binding Protein Li 70n，SERPINF1，Serpin F1
Anzahl der inverkehr gebrachten Arzneimittel	0
Anzahl der klinischen Arzneimittel	2
Höchste Forschungs- und Entwicklungsphase	Phase 3 Clinical

Serpin F1 Produktliste

Attribut
Protein (1)
Produktbibliothek
Online (1)
Spezies
Human (1)
Etikett
His Tag (1)
Marker
Unconjugated (1)

Produktnummer	Spezies	Expressionssystem	Produktbeschreibung	Proteinstruktur	Reinheit	Eigenschaften	Vorbestellen/Bestellen
SE1-H5221	Human	HEK293	Human Serpin F1 / PEDF Protein, His Tag				In den Warenkorb legen

Gesamtmenge1

Serpin F1 Molekülhintergrund

erpin F1 (SERPINF1) is also known as Pigment epithelium-derived factor (PEDF), Cell proliferation-inducing gene 35 protein (PIG35). Serpin F1 belongs to the serpin family. Serpin F1 is expressed in quiescent cells. PEDF has a variety of functions including antiangiogenic, antitumorigenic, and neurotrophic properties. Endothelial cell migration is inhibited by SERPINF1/ PEDF. PEDF / SERPINF1 suppresses retinal neovascularization and endothelial cell proliferation. PEDF is also responsible for apoptosis of endothelial cells either through the p38 MAPK pathway or through the FAS/FASL pathway. PEDF also displays neurotrophic functions.

Serpin F1 Molekülalias

SERPINF1,Serpin F1,PEDF,PIG35,EPC-1

Klinische Arzneimittelinformation

Englischer Name	Forschungscode	Forschungsphase	Firma	Indikationen	Klinische Studie
BRM-421	BRM-421	Phase 3 Clinical	Brim Biotechnology Co Ltd	Dry Eye Syndromes; Keratoconjunctivitis Sicca; Xerophthalmia	Details
DVC1-0401	DVC1-0401	Phase 2 Clinical	Id Pharma, Kyushu University	Retinitis Pigmentosa	Details