ROBO4

ROBO4 Produktliste

Attribut
Protein (3)
Produktbibliothek
Online (3)
Spezies
Human (2)Mouse (1)
Etikett
His Tag & Avi Tag (1)His Tag (2)
Marker
Biotin-labeled (1)Unconjugated (2)

Produktnummer	Spezies	Expressionssystem	Produktbeschreibung	Vorbestellen/Bestellen
RO4-H52H3	Human	HEK293	Human ROBO4 Protein, His Tag (MALS verified)	In den Warenkorb legen
RO4-H82E3	Human	HEK293	Biotinylated Human ROBO4 Protein, His,Avitag™ (MALS verified)	In den Warenkorb legen
RO4-M52H3	Mouse	HEK293	Mouse ROBO4 Protein, His Tag (MALS verified)	In den Warenkorb legen

Gesamtmenge3

ROBO4 Molekülhintergrund

Roundabout homolog 4 (ROBO4) is also known as Magic roundabout (MRB) and ECSM4, which belongs to the immunoglobulin superfamily or ROBO family. ROBO4 contains 2 fibronectin type-III domains and 2 Ig-like C2-type (immunoglobulin-like) domains. ROBO4 is specifically expressed in endothelial cells and is also expressed at sites of angiogenesis in different tumor types. ROBO4 / MRB is the receptor for Slit proteins, at least for SLIT2, and seems to be involved in angiogenesis and vascular patterning. ROBO-4 may mediate the inhibition of primary endothelial cell migration by Slit proteins.