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RNF43

RNF43

RNF43 Overview

Molecule Name
E3 ubiquitin-protein ligase RNF43
Drug Development Progress
Drugs in Clinical Trials1
Approved Drugs0
Highest Development StagePhase 1 Clinical
Target Synonym
Background
E3 ubiquitin-protein ligase that acts as a negative regulator of the Wnt signaling pathway by mediating the ubiquitination, endocytosis and subsequent degradation of Wnt receptor complex components Frizzled. Acts on both canonical and non-canonical Wnt signaling pathway. Along with RSPO2 and ZNRF3, constitutes a master switch that governs limb specification (By similarity)

RNF43 Product List

Species
  • Human（1）
Tag
  • Fc Tag（1）
Host
  • HEK293（1）
Conjugate
  • Unconjugated（1）
Grade
  • RUO（1）
Low Endotoxin
  • No（1）
MoleculeCat. No.Product NameSpeciesHostStructurePurityActivitySize&Price
RNF43
RN3-H5256
Human RNF43 Protein, Fc Tag (MALS verified)
Human
HEK293
MALSSDS-PAGE
ELISA

$360.00

100ug
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Clinical Drug Information

English NameResearch CodeHighest Development StageCompanyIndicationClinical Trial
SZN-043SZN-043; SWEETS-1Phase 1 ClinicalSurrozen Inc
Hepatitis, Alcoholic; Liver Cirrhosis
Details
Customer Reviews