Properdin

Properdin Molekülinformation

Englischer Name	Properdin	Anzahl der inverkehr gebrachten Arzneimittel	0
Anzahl der klinischen Arzneimittel	2	Target-Alias	Complement factor P，CFP
Höchste Forschungs- und Entwicklungsphase	Phase 2 Clinical

Englischer Name	Properdin
Target-Alias	Complement factor P，CFP
Anzahl der inverkehr gebrachten Arzneimittel	0
Anzahl der klinischen Arzneimittel	2
Höchste Forschungs- und Entwicklungsphase	Phase 2 Clinical

Properdin Produktliste

Attribut
Protein (3)
Produktbibliothek
Online (3)
Spezies
Human (1)Mouse (1)Rhesus macaque (1)
Etikett
His Tag (3)
Marker
Unconjugated (3)

Produktnummer	Spezies	Expressionssystem	Produktbeschreibung	Vorbestellen/Bestellen
HOT PRN-H52H3	Human	HEK293	Human Properdin Protein, His Tag	In den Warenkorb legen
PRN-M52H5	Mouse	HEK293	Mouse Properdin Protein, His Tag	In den Warenkorb legen
PRN-R52H6	Rhesus macaque	HEK293	Rhesus macaque Properdin Protein, His Tag	In den Warenkorb legen

Gesamtmenge3

Properdin Molekülhintergrund

Properdin is also known as Complement factor P, CFP, PFC, a positive regulator of the alternate pathway of complement. It binds to and stabilizes the C3- and C5-convertase enzyme complexes. Properdin is produced by many different leukocyte subsets and circulates as cyclic oligomers of monomeric subunits. Properdin on platelet/granulocyte aggregates(PGA) formation are tightly regulated by Factor H, properdin enhances PGA formation via increased production of C5a, and that inhibition of properdin function has therapeutic potential to limit thromboinflammation in diseases characterized by increased PGA formation.

Properdin Molekülalias

Properdin,Complement factor P,CFP,PFC

Klinische Arzneimittelinformation

Englischer Name	Forschungscode	Forschungsphase	Firma	Indikationen	Klinische Studie
Tarperprumig	ALXN-1820	Phase 2 Clinical	Alexion Pharmaceuticals Inc	Anemia, Sickle Cell; Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis	Details
NM-5072	NM5072; NM-5072	Phase 1 Clinical	NovelMed Therapeutics Inc	Atypical Hemolytic Uremic Syndrome; Eye Diseases; Hemoglobinuria, Paroxysmal	Details