PROCR Molekülinformation
Molecule Name
Endothelial protein C receptor
Molekülalias
PROCR,EPCR,CD201,APC receptor,CCCA,CCD41
Drug Development Progress
Anzahl der klinischen Arzneimittel0
Anzahl der inverkehr gebrachten Arzneimittel0
Höchste Forschungs- und Entwicklungsphase
Target-Alias
Cell Cycle， Centrosome-Associated Protein，CCCA，EPCR，CD201，PROCR，Endothelial Cell Protein C Receptor，Protein C Receptor，Centrocyclin，CCD41，Endothelial protein C receptor，APC Receptor，Protein C Receptor， Endothelial，Activated Protein C Receptor，CD201 Antigen
Molekülhintergrund
Endothelial protein C receptor (PROCR) is also known as Activated protein C receptor (APC receptor), Endothelial cell protein C receptor, CD antigen CD201. PROCR / EPCR / CD201 is a N-glycosylated protein, with a soluble form exists. PROCR is probably released by a metalloprotease. PROCR seems to have the same activity as the membrane-bound form. PROCR / EPCR / CD201 is expressed strongly in the endothelial cells of arteries and veins in heart and lung. PROCR binds activated protein C and enhances protein C activation by the thrombin - thrombomodulin complex. PROCR plays a role in the protein C pathway controlling blood coagulation.
PROCR Produktliste
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