Plectin

Plectin

Plectin Molekülinformation

Molecule Name
Plectin
Molekülalias
Plectin,PLTN,PCN,HD1,Hemidesmosomal protein 1,PLEC1
Drug Development Progress
Anzahl der klinischen Arzneimittel1
Anzahl der inverkehr gebrachten Arzneimittel0
Höchste Forschungs- und EntwicklungsphasePhase 2 Clinical
Target-Alias
PLTN,Hemidesmosomal protein 1
Molekülhintergrund
Interlinks intermediate filaments with microtubules and microfilaments and anchors intermediate filaments to desmosomes or hemidesmosomes. Could also bind muscle proteins such as actin to membrane complexes in muscle. May be involved not only in the filaments network, but also in the regulation of their dynamics. Structural component of muscle. Isoform 9 plays a major role in the maintenance of myofiber integrity.

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Klinische Arzneimittelinformation

Englischer NameForschungscodeForschungsphaseFirmaIndikationenKlinische Studie
IbentatugZB-131Phase 2 ClinicalZielbio Inc
Biliary Tract Neoplasms; Carcinoma, Pancreatic Ductal; Cystadenocarcinoma, Serous; Ovarian Neoplasms; Solid tumours
Details