PD-L2

PD-L2 Molekülinformation

Englischer Name	Programmed death-ligand 2	Anzahl der inverkehr gebrachten Arzneimittel	0
Anzahl der klinischen Arzneimittel	3	Target-Alias	PDCD1LG2，PDL2，Programmed death ligand 2，CD273，Butyrophilin B7-DC，PD-1 ligand 2，B7-DC，BA574F11.2，PDCD1L2，CD273 Antigen，B7DC，Btdc，B7 Dendritic Cell Molecule，PD-1-Ligand 2，PDCD1 ligand 2，Programmed cell death 1 ligand 2
Höchste Forschungs- und Entwicklungsphase	Phase 3 Clinical

Englischer Name	Programmed death-ligand 2
Target-Alias	PDCD1LG2，PDL2，Programmed death ligand 2，CD273，Butyrophilin B7-DC，PD-1 ligand 2，B7-DC，BA574F11.2，PDCD1L2，CD273 Antigen，B7DC，Btdc，B7 Dendritic Cell Molecule，PD-1-Ligand 2，PDCD1 ligand 2，Programmed cell death 1 ligand 2
Anzahl der inverkehr gebrachten Arzneimittel	0
Anzahl der klinischen Arzneimittel	3
Höchste Forschungs- und Entwicklungsphase	Phase 3 Clinical

PD-L2 Produktliste

Attribut
Protein (8)
Produktbibliothek
Online (8)
Spezies
Human (5)Mouse (3)
Etikett
His Tag (2)Fc Tag (2)Mouse IgG Fc Tag (1)His Tag & Avi Tag (2)Fc Tag & Avi Tag (1)
Marker
Unconjugated (5)Biotin-labeled (3)

Produktnummer	Spezies	Expressionssystem	Produktbeschreibung	Vorbestellen/Bestellen
HOT PD2-H5220	Human	HEK293	Human PD-L2 / B7-DC Protein, His Tag, low endotoxin (SPR verified)	In den Warenkorb legen
HOT PD2-H82E8	Human	HEK293	Biotinylated Human PD-L2 / B7-DC Protein, Avitag™,His Tag (recommended for biopanning)	In den Warenkorb legen
HOT PD2-H82F6	Human	HEK293	Biotinylated Human PD-L2 / B7-DC Protein, Fc,Avitag™ (MALS verified)	In den Warenkorb legen
HOT PD2-M52E3	Mouse	HEK293	Mouse PD-L2 / B7-DC Protein, His Tag (MALS verified)	In den Warenkorb legen
HOT PD2-M82E3	Mouse	HEK293	Biotinylated Mouse PD-L2 / B7-DC Protein, His,Avitag™ (MALS verified)	In den Warenkorb legen
PD2-H5251	Human	HEK293	Human PD-L2 / B7-DC Protein, Fc Tag, low endotoxin (MALS & BLI verified)	In den Warenkorb legen
PD2-H52A5	Human	HEK293	Human PD-L2 / B7-DC Protein, Mouse IgG1 Fc Tag	In den Warenkorb legen
PD2-M5254	Mouse	HEK293	Mouse PD-L2 / B7-DC Protein, Fc Tag	In den Warenkorb legen

Gesamtmenge8

Produktanfrage

PD-L2 Molekülhintergrund

Programmed cell death 1 ligand 2 (PD-L2 or PDCD1 ligand 2) is also known as Butyrophilin B7-DC, CD antigen CD273, which belongs to the immunoglobulin superfamily or BTN/MOG family. The expression of PD-L2 is up-regulated by IFNG/IFN-gamma stimulation in monocytes and induced on dendritic cells grown from peripheral blood mononuclear cells with CSF2 and IL-4. PD-L2 Involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. PD-L2 interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production.

PD-L2 Molekülalias

PDL2,PD-L2,Butyrophilin B7-DC,CD273,PDCD1 ligand 2,PDCD1L2,PDCD1LG2

Klinische Arzneimittelinformation

Englischer Name	Forschungscode	Forschungsphase	Firma	Indikationen	Klinische Studie
CA-170	CA-170; AUPM-170	Phase 3 Clinical	Aurigene	Carcinoma, Non-Small-Cell Lung; Neoplasms; Solid tumours	Details
IMGS-001	IMGS-001	Phase 1 Clinical	The University Of Texas MD Anderson Cancer Center	Colorectal Neoplasms; Neoplasms; Prostatic Neoplasms; Solid tumours; Triple Negative Breast Neoplasms	Details
68Ga-Mirc415		Clinical	Beijing Cancer Hospital	Lung Neoplasms	Details

Produktrezensionen

1***32019-10-11
0Menschen mögen
Human PD-L2 / B7-DC Protein, His Tag, low endotoxin (SPR verified)
ACROBiosystem's proteins have high purity. They totally meet our requirements. Most importantly, repeatability among batches is very good, and the quality control is great. Thank you!
1***22019-10-12
1Menschen mögen
Human PD-L2 / B7-DC Protein, Fc Tag, low endotoxin (MALS & BLI verified)
I purchased the PD-L2 protein for ELISA related experiments. Coating the protein into a well plate, and then adding antibody molecules to incubate with biotin-PD1. I could obtain good stable and repeatable data.