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PAR2

PAR2 Molekülinformation

Englischer NameProtease-activated receptor-2Anzahl der inverkehr gebrachten Arzneimittel0
Anzahl der klinischen Arzneimittel3Target-AliasReceptor, PAR-2,F2RL1,Thrombin receptor-like 1,G-protein coupled receptor 11,F2R Like Trypsin Receptor 1,PAR2,GPR11,Protease-Activated Receptor 2,Coagulation Factor II (Thrombin) Receptor-Like 1,Proteinase-Activated Receptor-2,Proteinase-activated receptor 2,Coagulation factor II receptor-like 1
Höchste Forschungs- und EntwicklungsphasePhase 2 Clinical
Englischer NameProtease-activated receptor-2
Target-AliasReceptor, PAR-2,F2RL1,Thrombin receptor-like 1,G-protein coupled receptor 11,F2R Like Trypsin Receptor 1,PAR2,GPR11,Protease-Activated Receptor 2,Coagulation Factor II (Thrombin) Receptor-Like 1,Proteinase-Activated Receptor-2,Proteinase-activated receptor 2,Coagulation factor II receptor-like 1
Anzahl der inverkehr gebrachten Arzneimittel0
Anzahl der klinischen Arzneimittel3
Höchste Forschungs- und EntwicklungsphasePhase 2 Clinical

PAR2 Produktliste

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    Protein (1)

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    Online (1)

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    Human (1)

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    - (1)

  • Marker

    Unconjugated (1)

ProduktnummerSpeziesExpressionssystemProduktbeschreibungProteinstrukturReinheitEigenschaftenVorbestellen/Bestellen
PA2-H52P7
Human
HEK293
Human PAR2 Full Length Protein (VLP) In den Warenkorb legen
Gesamtmenge1
  • 1

PAR2 Molekülhintergrund

This gene encodes a member of the G-protein coupled receptor 1 family of proteins. The encoded cell surface receptor is activated through proteolytic cleavage of its extracellular amino terminus, resulting in a new amino terminus that acts as a tethered ligand that binds to an extracellular loop domain. Activation of the receptor has been shown to stimulate vascular smooth muscle relaxation, dilate blood vessels, increase blood flow, and lower blood pressure. This protein is also important in the inflammatory response, as well as innate and adaptive immunity. [provided by RefSeq, Jun 2016]

PAR2 Molekülalias

PAR2

Klinische Arzneimittelinformation

Englischer NameForschungscodeForschungsphaseFirmaIndikationenKlinische Studie
MEDI-0618MEDI-0618; MEDI0618; ABBV-2002; ABBV2002Phase 2 ClinicalAstrazeneca PlcChronic Pain; Migraine Disorders
Details
TEV-56192TEV-56192Phase 1 ClinicalTeva Pharmaceutical Industries LtdNervous System Diseases
Details
OA-235iOA-235iPhase 1 ClinicalOasis Pharmaceuticals LLCMetabolic Dysfunction-Associated Steatotic Liver Disease
Details
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