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StartseiteAlle MoleküleORF8
ORF8
ORF8 Produktliste
- Attribut
Protein (1)
- Produktbibliothek
Online (1)
- Spezies
SARS-CoV-2 (1)
- Etikett
His Tag (1)
- Marker
Unconjugated (1)
| Produktnummer | Spezies | Expressionssystem | Produktbeschreibung | Proteinstruktur | Reinheit | Eigenschaften | Vorbestellen/Bestellen |
|---|---|---|---|---|---|---|---|
OR8-C52H1 | SARS-CoV-2 | HEK293 | SARS-CoV-2 ORF8 Protein, His Tag (MALS verified) |  |  |  In den Warenkorb legen |
Gesamtmenge1
- 1
ORF8 Molekülhintergrund
The viral protein encoded by open reading frame 8 (ORF8) of SARS-CoV-2, which shares the least homology with SARS-CoV among all viral proteins, directly interacts with MHC-Ι molecules and mediates their down-regulation. In ORF8-expressing cells, MHC-Ι molecules are selectively targeted for lysosomal degradation via autophagy. Thus, SARS-CoV-2–infected cells are much less sensitive to lysis by cytotoxic T lymphocytes.
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