NRG1 Beta 1

NRG1 Beta 1 Molekülinformation

Englischer Name	Neuregulin-1	Anzahl der inverkehr gebrachten Arzneimittel	0
Anzahl der klinischen Arzneimittel	0	Target-Alias	Sensory and motor neuron-derived factor，Pro-neuregulin-1， membrane-bound isoform，Glial growth factor，Neuregulin-1，Acetylcholine receptor-inducing activity，Pro-NRG1，ARIA，Breast cancer cell differentiation factor p45，Neu differentiation factor，Heregulin，HRG
Höchste Forschungs- und Entwicklungsphase	Preclinical

Englischer Name	Neuregulin-1
Target-Alias	Sensory and motor neuron-derived factor，Pro-neuregulin-1， membrane-bound isoform，Glial growth factor，Neuregulin-1，Acetylcholine receptor-inducing activity，Pro-NRG1，ARIA，Breast cancer cell differentiation factor p45，Neu differentiation factor，Heregulin，HRG
Anzahl der inverkehr gebrachten Arzneimittel	0
Anzahl der klinischen Arzneimittel	0
Höchste Forschungs- und Entwicklungsphase	Preclinical

NRG1 Beta 1 Produktliste

Attribut
Protein (2)
Produktbibliothek
Online (2)
Spezies
Human (2)
Etikett
Fc Tag (1)His Tag (1)
Marker
Unconjugated (2)

Produktnummer	Spezies	Expressionssystem	Produktbeschreibung	Proteinstruktur	Reinheit	Eigenschaften	Vorbestellen/Bestellen
NR1-H5246	Human	HEK293	Human NRG1 Beta 1 Protein, His Tag, premium grade				In den Warenkorb legen
NR1-H5268	Human	HEK293	Human NRG1 Beta 1 Protein, Fc Tag, premium grade				In den Warenkorb legen

Gesamtmenge2

NRG1 Beta 1 Molekülhintergrund

NRG1 is one of four proteins in the neuregulin family that act on the EGFR family of receptors. It is known that an extraordinary variety of different isoforms are produced from the NRG1 gene by alternative splicing. These isoforms include heregulins (HRGs), glial growth factors (GGFs) and sensory and motor neuron-derived factor (SMDF). They are tissue-specific and differ significantly in their structure. The HRG isoforms all contain immunoglobulin (Ig) and epidermal growth factor-like (EGF-like) domains. GGF and GGF2 isoforms contain a kringle-like sequence plus Ig and EGF-like domains; and the SMDF isoform shares only the EGF-like domain with other isoforms. The receptors for all NRG1 isoforms are the ERBB family of tyrosine kinase transmembrane receptors. Through their displayed interaction with ERBB receptors, NRG1 isoforms induce the growth and differentiation of epithelial, neuronal, glial, and other types of cells.