NGFR
NGFR Molekülinformation
| Englischer Name | Low affinity neurotrophin receptor p75NTR | Anzahl der inverkehr gebrachten Arzneimittel | 0 |
| Anzahl der klinischen Arzneimittel | 3 | Target-Alias | Gp80-LNGFR，P75NTR，CD271 Antigen，Low-Affinity Nerve Growth Factor Receptor，Tumor Necrosis Factor Receptor Superfamily Member 16，Low Affinity Nerve Growth Factor Receptor，Low Affinity Neurotrophin Receptor P75NTR，Nerve Growth Factor Receptor (TNFR Superfamily， Member 16)，TNFR Superfamily， Member 16，Nerve Growth Factor Receptor，P75 ICD，P75(NTR)，TNFRSF16，CD271 |
| Höchste Forschungs- und Entwicklungsphase | Phase 2 Clinical | ||
| Englischer Name | Low affinity neurotrophin receptor p75NTR |
| Target-Alias | Gp80-LNGFR，P75NTR，CD271 Antigen，Low-Affinity Nerve Growth Factor Receptor，Tumor Necrosis Factor Receptor Superfamily Member 16，Low Affinity Nerve Growth Factor Receptor，Low Affinity Neurotrophin Receptor P75NTR，Nerve Growth Factor Receptor (TNFR Superfamily， Member 16)，TNFR Superfamily， Member 16，Nerve Growth Factor Receptor，P75 ICD，P75(NTR)，TNFRSF16，CD271 |
| Anzahl der inverkehr gebrachten Arzneimittel | 0 |
| Anzahl der klinischen Arzneimittel | 3 |
| Höchste Forschungs- und Entwicklungsphase | Phase 2 Clinical |
NGFR Produktliste
- Attribut
Protein (1)Cell (1)
- Produktbibliothek
Online (2)
- Spezies
Human (2)
- Etikett
Fc Tag (1)- (1)
- Marker
Unconjugated (1)- (1)
| Produktnummer | Spezies | Expressionssystem | Produktbeschreibung | Proteinstruktur | Reinheit | Eigenschaften | Vorbestellen/Bestellen |
|---|---|---|---|---|---|---|---|
 Human | HEK293 | HEK293/Human NGFR Stable Cell Line |  |  In den Warenkorb legen | |||
| Human | HEK293 | Human NGFR / TNFRSF16 Protein, Fc Tag (MALS & BLI verified) |  |  |  | In den Warenkorb legen |
Gesamtmenge2
- 1
NGFR Molekülhintergrund
The p75 neurotrophin receptor (p75NTR) was originally identified as a low-affinity receptor for neurotrophins(NGF R).p75NTR is a neurotrophic factor receptor. Neurotrophic factor receptors bind Neurotrophins including Nerve growth factor, Neurotrophin-3, Brain-derived neurotrophic factor, and Neurotrophin-4. All neurotrophins bind to p75NTR. This also includes the immature pro-neurotrophin forms. Neurotrophic factor receptors, including p75NTR, are responsible for ensuring a proper density to target ratio of developing neurons, refining broader maps in development into precise connections. p75NTR is involved in pathways that promote neuronal survival and neuronal death.
NGFR Molekülalias
tumor necrosis factor receptor superfamily member 16; CD271; Gp80-LNGFR; member 16 nerve growth factor receptor; p75 ICD; p75 NTR
Klinische Arzneimittelinformation
| Englischer Name | Forschungscode | Forschungsphase | Firma | Indikationen | Klinische Studie |
|---|---|---|---|---|---|
| LM11A-31 | LM11A-31; LM11A-31-BHS | Phase 2 Clinical | Pharmatrophix Inc | Alzheimer Disease; Supranuclear Palsy, Progressive | Details |
| Recombinant human nerve growth factor (Xintrum Pharmacouticals) | rh-NGF; ZX1305; ZX-1305; ZX1305E; ZX-1305-E | Phase 2 Clinical | Jiangsu Zhongxin Pharmaceutical Co Ltd | Glaucoma, Open-Angle; Keratitis; Optic Nerve Injuries | Details |
| Recombinant Human Nerve Growth Factor (Kerun Biopharmaceutical) | Phase 1 Clinical | Chongqing Kerun Biologic Pharmaceutical Development Co Ltd | Keratitis; Xerophthalmia | Details |
- Molekülinformation
- Produktliste
- Klinische Arzneimittelinformation