Neuropilin-2

Neuropilin-2 Molekülinformation

Englischer Name	Neuropilin 2	Anzahl der inverkehr gebrachten Arzneimittel	0
Anzahl der klinischen Arzneimittel	1	Target-Alias	Neuropilin-2，Vascular endothelial cell growth factor 165 receptor 2，NPN2，NP2，Neuropilin-2a(22)，Neuropilin-2b(0)，VEGF165R2，PRO2714，Neuropilin-2a(17)，Receptor For VEGF165 And Semaphorins Class3
Höchste Forschungs- und Entwicklungsphase	Phase 3 Clinical

Englischer Name	Neuropilin 2
Target-Alias	Neuropilin-2，Vascular endothelial cell growth factor 165 receptor 2，NPN2，NP2，Neuropilin-2a(22)，Neuropilin-2b(0)，VEGF165R2，PRO2714，Neuropilin-2a(17)，Receptor For VEGF165 And Semaphorins Class3
Anzahl der inverkehr gebrachten Arzneimittel	0
Anzahl der klinischen Arzneimittel	1
Höchste Forschungs- und Entwicklungsphase	Phase 3 Clinical

Neuropilin-2 Produktliste

Attribut
Protein (2)
Produktbibliothek
Online (2)
Spezies
Human (2)
Etikett
His Tag (1)His Tag & Avi Tag (1)
Marker
Unconjugated (1)Biotin-labeled (1)

Produktnummer	Spezies	Expressionssystem	Produktbeschreibung	Proteinstruktur	Reinheit	Eigenschaften	Vorbestellen/Bestellen
NR2-H52H3	Human	HEK293	Human Neuropilin-2 / NRP2 Protein, His Tag (MALS verified)				In den Warenkorb legen
NR2-H82E3	Human	HEK293	Biotinylated Human Neuropilin-2 / NRP2 Protein, His,Avitag™ (MALS verified)				In den Warenkorb legen

Gesamtmenge2

Neuropilin-2 Molekülhintergrund

Neuropilin-1 (Npn-1, previously known as neuropilin) and Neuropilin-2 (previously known as Npn-1-related molecule) are type I transmembrane proteins that bind distinct members of the class III secreted semaphorin subfamily that are implicated in repulsive axon guidance. Neuropilin extracellular domains contain two CUB (complement-binding) domains, two domains with homology to coagulation factors V and VIII, and a MAM (meprin) domain. In the absence of ligands, neuropilins can form homo- and hetero-oligomers via their MAM domains. Expression in developing neurons of the central and peripheral nervous systems is somewhat overlapping but distinct. Npn-1 and Npn-2 are also receptors for VEGF165 on endothelial and tumor cells.

Neuropilin-2 Molekülalias

Neuropilin-2,NRP2,VEGF165R2,Neuropilin2,Vascular endothelial cell growth factor 165 receptor 2

Klinische Arzneimittelinformation

Englischer Name	Forschungscode	Forschungsphase	Firma	Indikationen	Klinische Studie
Efzofitimod	ATYR-1923; KRP-R120	Phase 3 Clinical	Atyr Pharma	Coronavirus Disease 2019 (COVID-19); Lung Diseases, Interstitial; Sarcoidosis, Pulmonary	Details