Neuropilin-1

Neuropilin-1 Molekülinformation

Englischer Name	Neuropilin-1	Anzahl der inverkehr gebrachten Arzneimittel	0
Anzahl der klinischen Arzneimittel	1	Target-Alias	BDCA4，NP1，Neuropilin-1，NRP1，CD304，VEGF165R，Neuropilin 1，Vascular Endothelial Cell Growth Factor 165 Receptor，NRP，Transmembrane Receptor，CD304 Antigen
Höchste Forschungs- und Entwicklungsphase	Phase 2 Clinical

Englischer Name	Neuropilin-1
Target-Alias	BDCA4，NP1，Neuropilin-1，NRP1，CD304，VEGF165R，Neuropilin 1，Vascular Endothelial Cell Growth Factor 165 Receptor，NRP，Transmembrane Receptor，CD304 Antigen
Anzahl der inverkehr gebrachten Arzneimittel	0
Anzahl der klinischen Arzneimittel	1
Höchste Forschungs- und Entwicklungsphase	Phase 2 Clinical

Neuropilin-1 Produktliste

Attribut
Protein (5)
Produktbibliothek
Online (5)
Spezies
Human (3)Mouse (2)
Etikett
His Tag (2)Fc Tag (1)His Tag & Avi Tag (1)Mouse IgG Fc Tag (1)
Marker
Unconjugated (4)Biotin-labeled (1)

Produktnummer	Spezies	Expressionssystem	Produktbeschreibung	Vorbestellen/Bestellen
HOT NR1-H5228	Human	HEK293	Human Neuropilin-1 / NRP1 / CD304 Protein, His Tag	In den Warenkorb legen
HOT NR1-H5252	Human	HEK293	Human Neuropilin-1 / NRP1 / CD304 Protein, Fc Tag	In den Warenkorb legen
HOT NR1-H82E3	Human	HEK293	Biotinylated Human Neuropilin-1 / NRP1 / CD304 Protein, His,Avitag™	In den Warenkorb legen
HOT NR1-M5254	Mouse	HEK293	Mouse Neuropilin-1 / NRP1 / CD304 Protein, Mouse IgG2a Fc Tag, low endotoxin	In den Warenkorb legen
NR1-M52H3	Mouse	HEK293	Mouse Neuropilin-1 / NRP1 / CD304 Protein, His Tag	In den Warenkorb legen

Gesamtmenge5

Neuropilin-1 Molekülhintergrund

Neuropilin-1 (NRP1) is also known as Vascular endothelial cell growth factor 165 receptor (VEGF165R), CD antigen CD304, which belongs to the neuropilin family. The membrane-bound isoform 1 is a receptor involved in the development of the cardiovascular system, in angiogenesis, in the formation of certain neuronal circuits and in organogenesis outside the nervous system. It mediates the chemorepulsant activity of semaphorins. It binds to semaphorin 3A, The PLGF-2 isoform of PGF, The VEGF-165 isoform of VEGF and VEGF-B. Coexpression with KDR results in increased VEGF-165 binding to KDR as well as increased chemotaxis. It may regulate VEGF-induced angiogenesis. The soluble isoform 2 binds VEGF-165 and appears to inhibit its binding to cells.

Neuropilin-1 Molekülalias

NRP1,Neuropilin-1,NRP,VEGF165R,CD304

Klinische Arzneimittelinformation

Englischer Name	Forschungscode	Forschungsphase	Firma	Indikationen	Klinische Studie
Certepetide	CEND-1; iRGD; CIND-1; LSTA1; QLC12102; LSTA-1	Phase 2 Clinical	Drugcendr Inc	Appendiceal Neoplasms; Bile Duct Neoplasms; Carcinoma, Ovarian Epithelial; Carcinoma, Pancreatic Ductal; Cholangiocarcinoma; Colonic Neoplasms; Colorectal Neoplasms; Gallbladder Neoplasms; Neoplasm Metastasis; Pancreatic Neoplasms; Triple Negative Breast Neoplasms	Details