Netrin-1

Netrin-1 Molekülinformation

Englischer Name	Netrin 1	Anzahl der inverkehr gebrachten Arzneimittel	0
Anzahl der klinischen Arzneimittel	1	Target-Alias	Netrin-1，Netrin 1， Mouse， Homolog Of，MRMV4，Epididymis tissue protein Li 131P，NTN1L
Höchste Forschungs- und Entwicklungsphase	Phase 2 Clinical

Englischer Name	Netrin 1
Target-Alias	Netrin-1，Netrin 1， Mouse， Homolog Of，MRMV4，Epididymis tissue protein Li 131P，NTN1L
Anzahl der inverkehr gebrachten Arzneimittel	0
Anzahl der klinischen Arzneimittel	1
Höchste Forschungs- und Entwicklungsphase	Phase 2 Clinical

Netrin-1 Produktliste

Attribut
Protein (1)
Produktbibliothek
Online (1)
Spezies
Human (1)
Etikett
His Tag (1)
Marker
Unconjugated (1)

Produktnummer	Spezies	Expressionssystem	Produktbeschreibung	Proteinstruktur	Reinheit	Eigenschaften	Vorbestellen/Bestellen
NE1-H52H3	Human	HEK293	Human Netrin-1 Protein, His Tag				In den Warenkorb legen

Gesamtmenge1

Netrin-1 Molekülhintergrund

Netrins control guidance of CNS commissural axons and peripheral motor axons. Its association with either DCC or some UNC5 receptors will lead to axon attraction or repulsion, respectively. Binding to UNC5C might cause dissociation of UNC5C from polymerized TUBB3 in microtubules and thereby lead to increased microtubule dynamics and axon repulsion. Involved in dorsal root ganglion axon projection towards the spinal cord. It also serves as a survival factor via its association with its receptors which prevent the initiation of apoptosis. Involved in tumorigenesis by regulating apoptosis.

Netrin-1 Molekülalias

Netrin-1,NTN1,NTN1L,Netrin1,netrin 1

Klinische Arzneimittelinformation

Englischer Name	Forschungscode	Forschungsphase	Firma	Indikationen	Klinische Studie
NP-137	NP-137; NP-137R; NP137P	Phase 2 Clinical	Centre Leon Berard, Netris Pharma	Carcinoma, Hepatocellular; Carcinoma, Pancreatic Ductal; Endometrial Neoplasms; Pancreatic Neoplasms; Solid tumours; Uterine Cervical Neoplasms	Details